High Affinity Immunoglobulin Gamma Fc Receptor I

Preferred Label : High Affinity Immunoglobulin Gamma Fc Receptor I;

NCIt synonyms : Fc-Gamma RIA; Fc Gamma Receptor; Fc Gamma Receptor I A1; Fc-Gamma RI; IgG Fc Receptor I; CD64 Antigen; FCGR1A;

NCIt related terms : CD64;

NCIt definition : High affinity immunoglobulin gamma Fc receptor I (374 aa, 43 kDa) is encoded by the human FCGR1A gene. This protein is involved in the immune response and signal transduction.;

Details

Origin ID

C104238;

UMLS CUI

C3542421;

OMIM relation
- Fc fragment of igg receptor ia [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FCGR1A Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Fc-Gamma Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Antigen Processing [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients