GCG wt Allele - CISMeF

Preferred Label : GCG wt Allele;

NCIt synonyms : GLP2; GRPP; GCG; Glucagon wt Allele; GLP1; Glucagon-Like Peptide 1 Gene; Glicentin-Related Polypeptide Gene; Glucagon-Like Peptide 2 Gene;

NCIt definition : Human GCG wild-type allele is located in the vicinity of 2q24.2 and is approximately 9 kb in length. This allele, which encodes proglucagon protein, is involved in the stimulation of glycogen processing, gluconeogenesis and the absorption of nutrients by the gut.;

NCIt note : The GCG gene product is a precursor for glicentin, glicentin-related polypeptide (GRPP), oxyntomodulin (OXY, OXM), glucagon, glucagon-like peptide 1 (GLP-1), glucagon-like peptide 1(7-37) (GLP-1(7-37)), glucagon-like peptide 1(7-36)(GLP-1(7-36), and glucagon-like peptide 2 (GLP-2). (SwissProt);

GenBank Accession Number : NM_002054;

Details

Origin ID

C52414;

UMLS CUI

C1705879;

Automatic exact mappings (from CISMeF team)
- GCG [EDAM format]
- Glucagon [OMIM gene]
- Glucagon-like peptide 1 (substance) [SNOMED CT concept]
- Glucagon-like peptide 2 (substance) [SNOMED CT concept]
- Zinc finger gata-like protein 1 [OMIM gene]
- glucagon-like peptide 1 [MeSH Descriptor]
- glucagon-like peptide 2 [MeSH Descriptor]
OMIM relation
- Glucagon [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Hypoglycemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Gluconeogenic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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