glucagon-like peptide 1

Preferred Label : glucagon-like peptide 1;

MeSH definition : A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.;

MeSH synonym : glp-1; glp 1; glucagon like peptide 1; Glucagon-Like Peptide-1;

Registry Number MeSH : 89750-14-1;

Is substance : O;

Details

Origin ID

D052216;

UMLS CUI

C0061355;

ATC code(s)
- Glucagon-like peptide-1 (GLP-1) analogues [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- GATA-Type Zinc Finger Protein 1 [NCIt concept]
- GCG wt Allele [NCIt concept]
- Glucagon [OMIM gene]
- Glucagon-Like Peptide 1 [NCIt concept]
- Glucagon-like Peptide-1 Measurement [NCIt concept]
- Histone-Lysine N-Methyltransferase EHMT1 [NCIt concept]
- ZGLP1 wt Allele [NCIt concept]
- Zinc finger gata-like protein 1 [OMIM gene]
- glucagon [HGNC gene]
- glucagon like peptide 1 [Artificial nutrition thesaurus concept]
CISMeF manual mappings
- GLP-1 Mimetics [NCIt concept]
Currated CISMeF NLP mapping
- Glucagon-like peptide 1 (substance) [SNOMED CT concept]
- glucagon-like peptide 1 [SNOMED Notion]
Indexing information
- (2-sulfo-9-fluorenylmethoxycarbonyl)3-exendin-4 [MeSH Supplementary Concept]
- (Val8)GLP-1-Glu-PAL [MeSH Supplementary Concept]
- 1-(((3-hydroxy-1-adamantyl)amino)acetyl)-2-cyanopyrrolidine [MeSH Supplementary Concept]
- BIM 51077 [MeSH Supplementary Concept]
- Exenatide [MeSH Descriptor]
- ZP3022 [MeSH Supplementary Concept]
- exendin (1-9), Ser(2)- [MeSH Supplementary Concept]
- exendin (5-39) [MeSH Supplementary Concept]
- exendin (9-39) [MeSH Supplementary Concept]
- exendin 3 [MeSH Supplementary Concept]
- exendin receptor [MeSH Supplementary Concept]
- fluorescein-Trp(25)-exendin-4 [MeSH Supplementary Concept]
- heliodermin [MeSH Supplementary Concept]
- helospectin I [MeSH Supplementary Concept]
Pharmacological action(s)
- incretins [MeSH Descriptor]
Record concept(s)
- Glucagon-Like peptide 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- (Val8)GLP-1-Glu-PAL [MeSH Supplementary Concept]
- 5rolGLP-HV fusion peptide [MeSH Supplementary Concept]
- BIM 51077 [MeSH Supplementary Concept]
- BPI-3016 [MeSH Supplementary Concept]
- GLP-1(32-36)amide [MeSH Supplementary Concept]
- GW002 peptide [MeSH Supplementary Concept]
- LY307161 [MeSH Supplementary Concept]
- N-2-(4-fluorobenzamido)ethylmaleimide-EM 3106B [MeSH Supplementary Concept]
- SYGL-1 protein, C elegans [MeSH Supplementary Concept]
- ZP2495 [MeSH Supplementary Concept]
- acetyl-glucagon-like peptide 1 (7-34)-amide [MeSH Supplementary Concept]
- coumaglutide [MeSH Supplementary Concept]
- d-Ala(8) GLP-1(Lys(37))pentasaccharide [MeSH Supplementary Concept]
- glucagon-like peptide (7-37), valyl(10)- [MeSH Supplementary Concept]
- glucagon-like peptide 1 (1-36)amide [MeSH Supplementary Concept]
- glucagon-like peptide 1 (1-37) [MeSH Supplementary Concept]
- glucagon-like peptide 1 (7-36) [MeSH Supplementary Concept]
- glucagon-like peptide 1 (7-36), Ala(36)- [MeSH Supplementary Concept]
- glucagon-like peptide 1 (7-36), Val(8)- [MeSH Supplementary Concept]
- glucagon-like peptide 1 (7-36)amide [MeSH Supplementary Concept]
- glucagon-like peptide 1 (7-36)amide, Ser(8)- [MeSH Supplementary Concept]
- glucagon-like peptide 1 (7-37) [MeSH Supplementary Concept]
- glucagon-like peptide 1 (7-37)-proline, glycyl(2)- [MeSH Supplementary Concept]
- glucagon-like peptide-1 (7-36)amide, N-acetyl- [MeSH Supplementary Concept]
- glucagon-like peptide-1 (7-36)amide, N-pyroglutamyl- [MeSH Supplementary Concept]
- glucagon-like peptide-1 (9-36) [MeSH Supplementary Concept]
- glucagon-like peptide-1 (9-36)-amide [MeSH Supplementary Concept]
- glucagon-like peptide-1(28-36)amide [MeSH Supplementary Concept]
- rGLP-1 protein [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- Glucagon-like peptide 1 (substance) [SNOMED CT concept]
- glucagon-like peptide 1 [SNOMED Notion]

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