diphosphonates

Preferred Label : diphosphonates;

MeSH definition : Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.;

MeSH synonym : bisphosphonates; Bisphosphonate;

Wikipedia link : https://en.wikipedia.org/wiki/Bisphosphonate;

Is substance : O;

Details

Origin ID

D004164;

UMLS CUI

C0012544;

ATC code(s)
- bisphosphonates [ATC Code]
- bisphosphonates, combinations [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Base Pair Unit [NCIt concept]
- Binding Potential [NCIt concept]
- Bisphosphonates [ICD-11 Extension code]
- Blood Pressure [NCIt concept]
- Bullous pemphigoid [ICD-10 Sub-category (who)]
- Bullous pemphigoid [ORDO Disease]
- Bullous pemphigoid [MedDRA LLT]
- HP wt Allele [NCIt concept]
- bisphosphonates [ATC Code]
- bovine papular stomatitis [SNOMED Notion]
- bullous pemphigoid [SNOMED Notion]
Currated CISMeF NLP mapping
- Biphosphonate [NCIt concept]
- Bisphosphonate (substance) [SNOMED CT concept]
- Product containing bisphosphonate (product) [SNOMED CT concept]
- diphosphonate, nos [SNOMED Notion]
False automatic mappings
- British Pharmacopeia [NCIt concept]
Pharmacological action(s)
- bone density conservation agents [MeSH Descriptor]
Record concept(s)
- diphosphonates [MeSH concept]
Related MeSH Supplementary Concept(s)
- (((((4-hydroxy-4,4-diphosphonobutyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethanethiolate)oxorhenium(V) [MeSH Supplementary Concept]
- (2-(6-aminopurine-9-yl)-1-hydroxy-phosphine acyl ethyl)phosphonic acid [MeSH Supplementary Concept]
- (4-(((bis(phosphonopropyl))carbamoyl)methyl)-7,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl)acetic acid [MeSH Supplementary Concept]
- (90)Y-2,3-dicarboxypropane-1,1-diphosphonic acid [MeSH Supplementary Concept]
- (N-(2-((3-(3,3-diphosphonopropylcarbamoyl)propyl)-2-thioethylamino)acetyl)-2-aminoethanethiolate)oxorhenium(V) [MeSH Supplementary Concept]
- (N-(2-((4-((4-hydroxy-4,4-diphosphonobutyl)amino)-4-oxobutyl)-2-thioethylamino)acetyl)-2-aminoethanethiolate)oxorhenium(V) [MeSH Supplementary Concept]
- (fluorescein-6-carbonyloxy)acetoaminomethylene bisphosphonic acid [MeSH Supplementary Concept]
- (fluoro(hydroxyphenylphosphinyl)methyl)phosphonic acid [MeSH Supplementary Concept]
- 1,1-hydroxyoctanodiphosphonate [MeSH Supplementary Concept]
- 1,2-dipalmitoyloxypropyl-3-(2'-hydroxypropyl-3'-(1'',2''-dipalmitoylglycerol))biphosphonate [MeSH Supplementary Concept]
- 1-((N-(2,3,4,5,6-pentafluorocinnamoyl)-O-(2,6-dichlorobenzyl))tyrosyl)-4-(bis(diethoxyphosphono))methylaminiopiperidine [MeSH Supplementary Concept]
- 1-((N-heptylthio)ethyl)-1,1-bisphosphonate [MeSH Supplementary Concept]
- 1-aminoethylene diphosphonic acid [MeSH Supplementary Concept]
- 1-fluoro-2-(3-pyridinyl)ethylidene-1,1-bisphosphonic acid [MeSH Supplementary Concept]
- 1-fluorononylidene-1,1-bisphosphonic acid [MeSH Supplementary Concept]
- 1-hydroxy-2-(3-indolyl)ethane-1,1-diphosphonic acid [MeSH Supplementary Concept]
- 1-hydroxy-2-(4-aminophenyl)ethane-1,1-diphosphonic acid [MeSH Supplementary Concept]
- 1-hydroxy-2-(4-methyl-1H-imidazol-1-yl)-ethylidene-1,1-bisphosphonic acid [MeSH Supplementary Concept]
- 1-hydroxypentane-1,1-bisphosphonate [MeSH Supplementary Concept]
- 153Sm-BPAMD [MeSH Supplementary Concept]
- 2-(1-imidazole)-1-hydroxy-1,1'-ethylidenediphosphonic acid [MeSH Supplementary Concept]
- 2-(2-pyridyl)ethylidine-1,1-bisphosphonate [MeSH Supplementary Concept]
- 2-(3'-dimethylaminopyrazinio)ethylidene-1,1-bisphosphonic acid betaine [MeSH Supplementary Concept]
- 2-(3-picolyl)aminomethylene-1,1-bisphosphonic acid [MeSH Supplementary Concept]
- 2-(3-pyridinyl)-1-hydroxyethylidene-1,1-phosphonocarboxylic acid [MeSH Supplementary Concept]
- 2-iminopyrrolidone-5,5-diphosphonic acid [MeSH Supplementary Concept]
- 2-mercaptoethylidene-1,1-bisphosphonic acid [MeSH Supplementary Concept]
- 2-sulfonato-1,1-ethylidene bisphosphonic acid [MeSH Supplementary Concept]
- 3-astatobenzamido-N-3-hydroxypropylidene-3,3-bisphosphonate [MeSH Supplementary Concept]
- 3-iodobenzamido-N-3-hydroxypropylidene-3,3-bisphosphonate [MeSH Supplementary Concept]
- 4,4'-(carbonylbis(imino-3,1-phenylenecarbonylimino-3,1-(4-methylphenylene)carbonylimino))bis(1,3-xylene-alpha,alpha'-diphosphonic acid) [MeSH Supplementary Concept]
- 4,4-bisphosphono-2-(polyhydroxyl-1,2-dihydro-1,2-methanofullerene(6)-61-carboxamido)butyric acid [MeSH Supplementary Concept]
- 4-N,N-dimethylamino-1-hydroxybutylidene-1,1-diphosphonic acid [MeSH Supplementary Concept]
- 4-amino-1-hydroxybutylidene-1,1-diphosphonate [MeSH Supplementary Concept]
- 4-phosphono-2-(phosphonomethyl)butanoate [MeSH Supplementary Concept]
- 6-amino-1-hydroxyhexane-1,1-diphosphonate [MeSH Supplementary Concept]
- 68Ga NOTA-bisphosphonate [MeSH Supplementary Concept]
- 99mTc-incadronate [MeSH Supplementary Concept]
- AP21946 [MeSH Supplementary Concept]
- AP22188 [MeSH Supplementary Concept]
- AP22408 [MeSH Supplementary Concept]
- AP22409 [MeSH Supplementary Concept]
- BBR 3053 [MeSH Supplementary Concept]
- BP 7033 [MeSH Supplementary Concept]
- BPAMD ligand [MeSH Supplementary Concept]
- BPH1222 [MeSH Supplementary Concept]
- CGP 47072 [MeSH Supplementary Concept]
- CGP 58318 [MeSH Supplementary Concept]
- DP-R206 [MeSH Supplementary Concept]
- DTPA-1-hydroxy-3-aminopropane-1,1-diphosphonate [MeSH Supplementary Concept]
- DTPA-4-aminobutane-1,1-diphosphonate [MeSH Supplementary Concept]
- EB 1053 [MeSH Supplementary Concept]
- ER 27856 [MeSH Supplementary Concept]
- ER 28448 [MeSH Supplementary Concept]
- FR 78844 [MeSH Supplementary Concept]
- FYB-931 [MeSH Supplementary Concept]
- ISA 13-1 [MeSH Supplementary Concept]
- L 690330 [MeSH Supplementary Concept]
- L 690488 [MeSH Supplementary Concept]
- LE-Cl2MDP [MeSH Supplementary Concept]
- Me-BP7033 [MeSH Supplementary Concept]
- N,N-dimethylaminomethane diphosphonic acid [MeSH Supplementary Concept]
- N,N-dimethylenephosphonate-1-hydroxy-3-aminopropylidenediphosphonate [MeSH Supplementary Concept]
- N,N-dimethylenephosphonate-1-hydroxy-4-aminopropilydenediphosphonate [MeSH Supplementary Concept]
- N-(methyl(4-phenylbutyl))-3-aminopropyl-1-hydroxy-1,1-bisphosphonate [MeSH Supplementary Concept]
- N-iso-butoxycarbonylpamidronate tetramethyl ester [MeSH Supplementary Concept]
- NE 10244 [MeSH Supplementary Concept]
- NE 21650 [MeSH Supplementary Concept]
- NE 58051 [MeSH Supplementary Concept]
- P(1)-(7-hydroxy-6-(hydroxyethyl)-5-methoxy-4-methylphthalan-1-one-2-yl)-P(2)-(2-ethyladenosin-5'-yl)methylenebis(phosphonate) [MeSH Supplementary Concept]
- PNU 91638 [MeSH Supplementary Concept]
- SK&F 99085 [MeSH Supplementary Concept]
- SM 16896 [MeSH Supplementary Concept]
- SR 12813 [MeSH Supplementary Concept]
- SR 41319 [MeSH Supplementary Concept]
- TRK 530 [MeSH Supplementary Concept]
- YM 529 [MeSH Supplementary Concept]
- ZK 90695 [MeSH Supplementary Concept]
- acetylamino propylidene diphosphonic acid [MeSH Supplementary Concept]
- acrylolpamidronate [MeSH Supplementary Concept]
- adipoylbisphosphonic acid [MeSH Supplementary Concept]
- alpha-amino-(4-hydroxybenzylidene)diphosphonate [MeSH Supplementary Concept]
- aminobutane bisphosphonate [MeSH Supplementary Concept]
- aminomethane diphosphonate [MeSH Supplementary Concept]
- aminomethylene-bisphosphonic acid [MeSH Supplementary Concept]
- apomine [MeSH Supplementary Concept]
- azacycloheptane-2,2-diphosphonate [MeSH Supplementary Concept]
- belfosdil [MeSH Supplementary Concept]
- benzene-1,4-bis(aminomethylidene(bisphosphonic)) acid [MeSH Supplementary Concept]
- benzylmethylenediphosphonic acid [MeSH Supplementary Concept]
- bis(ethylenediamine)(1-hydroxy-1-(pyridinium-4-yl)methane-1,1-bisphosphonate)diplatinum(II) [MeSH Supplementary Concept]
- bis(isopropyl methyl)phosphonate [MeSH Supplementary Concept]
- bromomethylenebis(phosphonic acid) [MeSH Supplementary Concept]
- carbonyldiphosphonate [MeSH Supplementary Concept]
- cimadronate [MeSH Supplementary Concept]
- difluoromethylidene bisphosphonate [MeSH Supplementary Concept]
- digeranyl bisphosphonate [MeSH Supplementary Concept]
- diisopropyl methylenediphosphonate [MeSH Supplementary Concept]
- dimethylammonium hydrogen diphenyldiphosphonate [MeSH Supplementary Concept]
- dithioimidodiphosphinate [MeSH Supplementary Concept]
- ethane-1-hydroxy-1,1-bisphosphonate [MeSH Supplementary Concept]
- ethylidenediphosphonic acid [MeSH Supplementary Concept]
- hydroxymethanediphosphonic acid [MeSH Supplementary Concept]
- imidodiphosphonic acid [MeSH Supplementary Concept]
- isopentenyl methylenediphosphonate [MeSH Supplementary Concept]
- isopropylidenediphosphonic acid [MeSH Supplementary Concept]
- methotrexate bisphosphonate [MeSH Supplementary Concept]
- methylene diphosphonate [MeSH Supplementary Concept]
- naphthalene-1,5-bis(aminomethylidene(bisphosphonic)) acid [MeSH Supplementary Concept]
- olpadronic acid [MeSH Supplementary Concept]
- oxonia active [MeSH Supplementary Concept]
- pentane diphosphonate [MeSH Supplementary Concept]
- phenylacetate-bisphosphonate [MeSH Supplementary Concept]
- poly((acetone)tetraaqua(mu(6)-ethyl (dichloromethylene)diphosphonato)(mu(5)-ethyl (dichloromethylene)diphosphonato)tribarium(II)) [MeSH Supplementary Concept]
- prolyl-phenylalanyl-pamidronate [MeSH Supplementary Concept]
- propane-2,2-diphosphonic acid [MeSH Supplementary Concept]
- propylenediaminetetramethylene phosphonate [MeSH Supplementary Concept]
- stannous methylene diphosphonate [MeSH Supplementary Concept]
- suberoylbisphosphonic acid [MeSH Supplementary Concept]
- sulfonyldiphenyl-4,4'-bis(aminomethylidene(bisphosphonic)) acid [MeSH Supplementary Concept]
- technetium 99m 1-hydroxy-2-(2-isopropyl-1H-imidazole-1-yl)ethylidene-1,1-bisphosphonic acid [MeSH Supplementary Concept]
- technetium 99m 1-hydroxy-3-(1H-imidazol-1-yl)propane-1,1-diyldiphosphonic acid [MeSH Supplementary Concept]
- technetium 99m 1-hydroxy-4-(2-butyl-1H-imidazol-1-yl)butane-1,1-diyldiphosphonic acid [MeSH Supplementary Concept]
- technetium 99m 1-hydroxy-5-(2-butyl-1H-imidazol-1-yl)pentane-1,1-diyldiphosphonic acid [MeSH Supplementary Concept]
- technetium 99m 6-hydrazinopyridine-3-carboxylic acid-hydroxybisphosphonate [MeSH Supplementary Concept]
- technetium 99m hydroxyethylene-diphosphonate [MeSH Supplementary Concept]
- technetium 99m mercaptoacetylglycylglycylglycine-hydroxybisphosphonate [MeSH Supplementary Concept]
- technetium 99m methylene bisphosphonate [MeSH Supplementary Concept]
- technetium tc 99m (Sn)-imidodiphosphonic acid [MeSH Supplementary Concept]
- technetium tc 99m (sodium borohydride)-dimethylaminomethylene diphosphonate [MeSH Supplementary Concept]
- technetium tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid [MeSH Supplementary Concept]
- technetium tc 99m 1,2-diphosphonoethylene glycol [MeSH Supplementary Concept]
- technetium tc 99m 1-hydroxy-3-methylphosphinic-1,1-propanediphosphonic acid [MeSH Supplementary Concept]
- technetium tc 99m 3-amino-1-hydroxypropane-1,1-diphosphonate [MeSH Supplementary Concept]
- technetium tc 99m aminohexylidendiphosphonate [MeSH Supplementary Concept]
- technetium tc 99m carbonyl diphosphonic acid [MeSH Supplementary Concept]
- technetium tc 99m dihydroxymethylene diphosphonic acid [MeSH Supplementary Concept]
- technetium tc 99m dimethylaminodiphosphonate [MeSH Supplementary Concept]
- technetium tc 99m dimethylaminomethylene diphosphonate [MeSH Supplementary Concept]
- technetium tc 99m diphosphonate [MeSH Supplementary Concept]
- technetium tc 99m hexylidenaminodiphosphonate [MeSH Supplementary Concept]
- technetium tc 99m hydroxydiphosphonate [MeSH Supplementary Concept]
- technetium tc 99m-N-carboxyethylaminodimethyldiphosphonic acid [MeSH Supplementary Concept]
- technetium tc 99m-aminodimethyldiphosphonic acid [MeSH Supplementary Concept]
- technetium-99m-olpadronate [MeSH Supplementary Concept]
- tetra(pivaloyloxymethyl) (dichloromethylene)bisphosphonate [MeSH Supplementary Concept]
- tetraethyl anthracene-9,10-diyl-9,10-bis(phosphonate) [MeSH Supplementary Concept]
- tetrakispivaloyloxymethyl 2-(thiazole-2-ylamino)ethylidene-1,1-bisphosphonate [MeSH Supplementary Concept]
- tiludronic acid [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- Bisphosphonate-Associated osteonecrosis of the jaw [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Biphosphonate [NCIt concept]
- Bisphosphonate (substance) [SNOMED CT concept]
- Product containing bisphosphonate (product) [SNOMED CT concept]
- diphosphonate, nos [SNOMED Notion]

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