Denosumab - CISMeF

Preferred Label : Denosumab;

MeSH definition : A humanized monoclonal antibody and an inhibitor of the RANK LIGAND, which regulates OSTEOCLAST differentiation and bone remodeling. It is used as a BONE DENSITY CONSERVATION AGENT in the treatment of OSTEOPOROSIS.;

CISMeF synonym : 162, AMG;

MeSH hyponym : AMG 162; xgeva; prolia;

MeSH Related Number : 615258-40-7 (denosumab);

Is substance : O;

UNII : 4EQZ6YO2HI;

Details

Origin ID

D000069448;

UMLS CUI

C1690432;

ATC code(s)
- denosumab [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Denosumab [ICD-11 Extension code]
- Denosumab [SMS substance]
- Denosumab [Anticorps monoclonal]
- Product containing denosumab (medicinal product) [SNOMED CT concept]
- denosumab [International Nonproprietary Name]
Exact mapping(s) to DCI
- denosumab [International Nonproprietary Name]
Pharmacological action(s)
- bone density conservation agents [MeSH Descriptor]
Record concept(s)
- AMG 162 [MeSH concept]
- denosumab [MeSH concept]
- prolia [MeSH concept]
- xgeva [MeSH concept]
Related MeSH Supplementary Concept(s)
- QL1206 [MeSH Supplementary Concept]
See also
- rank ligand [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Denosumab [NCIt concept]
- Denosumab (substance) [SNOMED CT concept]
- Product containing denosumab (medicinal product) [SNOMED CT concept]
- denosumab [ATC Code]
- denosumab [International Nonproprietary Name]
Validated automatic mappings to BTNT
- denosumab [ATC Code]

Keyword's position in hierarchy(ies) :

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