Preferred Label : Raloxifene Hydrochloride;
MeSH definition : A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis
in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism
but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.;
MeSH synonym : keoxifene hydrochloride; Raloxifene HCl;
CISMeF synonym : 82640-04-8 (Raloxifene hydrochloride); ELi lilly brand of raloxifene; lilly brand of raloxifene; raloxifene lilly brand;
MeSH Hyperonym : raloxifene; Keoxifene;
MeSH hyponym : evista; LY-156758; LY-139481; LY139481; LY 139481; LY156758; LY 156758;
MeSH CAS label : methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-;
MeSH Related Number : raloxifene hydrochloride; 82640-04-8 (HCl); 84449-90-1 (Raloxifene); 82640-04-8 (raloxifene hydrochloride); 84449-90-1; YX9162EO3I;
Registry Number MeSH : 84449-90-1;
Related CAS MeSH : 4F86W47BR6 (Raloxifene hydrochloride);
Wikipedia link : https://en.wikipedia.org/wiki/Raloxifene;
Is substance : O;
UNII : YX9162EO3I; 4F86W47BR6;
InChIKey : GZUITABIAKMVPG-UHFFFAOYSA-N;
Origin ID : D020849;
UMLS CUI : C0618111;
ATC code(s)
Allowable qualifiers
CISMeF manual mappings
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis
in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism
but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
http://www.has-sante.fr/portail/jcms/c_1751307/fr/les-medicaments-de-losteoporose
2023
false
true
false
France
French
bone density conservation agents
osteoporosis
treatment outcome
alendronic acid
alendronate
guidelines for drug use
zoledronic acid
administration, oral
risedronic acid
denosumab
Raloxifene Hydrochloride
strontium ranelate
strontium ranelate
teriparatide
teriparatide
spinal fractures
hip fractures
costs and cost analysis
bone density conservation agents
drug costs
bone density
risk
osteoporosis, postmenopausal
adrenal cortex hormones
osteoporosis
osteoporotic fractures
alendronic acid and colecalciferol
drugs, generic
infusions, intravenous
risedronic acid, calcium and colecalciferol, sequential
injections, subcutaneous
raloxifene
algorithms
Adrenocortical steroid therapy
corticosteroid therapy
Risedronic Acid
Denosumab
diphosphonates
imidazoles
organometallic compounds
thiophenes
Zoledronic Acid
---
http://www.has-sante.fr/portail/jcms/c_2620159/fr/optruma
http://www.has-sante.fr/portail/jcms/c_1335883/optruma
http://www.has-sante.fr/portail/jcms/c_460193/optruma
2016
false
France
French
evaluation of the transparency committee
Raloxifene Hydrochloride
Raloxifene Hydrochloride
raloxifene
administration, oral
treatment outcome
bone density conservation agents
bone density conservation agents
insurance, health, reimbursement
osteoporosis, postmenopausal
spinal fractures
osteoporosis, postmenopausal
bone density
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68001016
2013
France
summary of product characteristics
Raloxifene Hydrochloride
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67050747
2012
France
summary of product characteristics
package leaflet
tablets
Raloxifene Hydrochloride
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67482059
2012
France
summary of product characteristics
package leaflet
raloxifene hydrochloride
Raloxifene Hydrochloride
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68161138
2012
France
summary of product characteristics
package leaflet
Raloxifene Hydrochloride
tablets
---
https://www.ema.europa.eu/medicines/human/EPAR/Optruma
2012
United Kingdom
English
French
syndication feed
Raloxifene Hydrochloride
osteoporosis, postmenopausal
osteoporosis, postmenopausal
bone density conservation agents
treatment outcome
raloxifene
bone density conservation agents
drug evaluation, preclinical
Raloxifene Hydrochloride
drug approval
drug labeling
drug interactions
pregnancy
breast feeding
selective estrogen receptor modulators
selective estrogen receptor modulators
administration, oral
tablets
spinal fractures
summary of product characteristics
drug evaluation
package leaflet
---
https://www.ema.europa.eu/medicines/human/EPAR/Raloxifene-Teva
2012
United Kingdom
French
English
syndication feed
administration, oral
Raloxifene Hydrochloride
tablets
Raloxifene Hydrochloride
drugs, generic
selective estrogen receptor modulators
selective estrogen receptor modulators
drug approval
drug labeling
treatment outcome
raloxifene
osteoporosis, postmenopausal
osteoporosis, postmenopausal
spinal fractures
adult
aged
bone density conservation agents
bone density conservation agents
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
summary of product characteristics
package leaflet
drug evaluation
---
http://www.has-sante.fr/portail/jcms/c_1335880/evista
http://www.has-sante.fr/portail/upload/docs/evamed/CT-9951_EVISTA_17102012_AVIS%202_RI_CT9951.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_460006
http://www.has-sante.fr/portail/display.jsp?id=c_398930
2012
France
French
tablets
Raloxifene Hydrochloride
osteoporosis, postmenopausal
osteoporosis, postmenopausal
treatment outcome
bone density conservation agents
Raloxifene Hydrochloride
bone density conservation agents
spinal fractures
drug utilization review
raloxifene
raloxifene hydrochloride
evaluation of the transparency committee
---
https://www.ema.europa.eu/medicines/human/EPAR/Evista
2012
United Kingdom
French
English
syndication feed
osteoporosis, postmenopausal
Raloxifene Hydrochloride
Raloxifene Hydrochloride
bone density conservation agents
bone density conservation agents
treatment outcome
drug evaluation
tablets
administration, oral
osteoporosis, postmenopausal
adult
aged
drug approval
drug labeling
drug interactions
drug evaluation, preclinical
spinal fractures
raloxifene
selective estrogen receptor modulators
selective estrogen receptor modulators
raloxifene hydrochloride
raloxifene hydrochloride
drug evaluation
summary of product characteristics
package leaflet
---
https://www.jle.com/fr/revues/medecine/bdc/e-docs/00/04/4A/67/resume.phtml?type=text.html
2009
France
French
journal article
selective estrogen receptor modulators
antineoplastic agents, hormonal
breast neoplasms
Raloxifene Hydrochloride
tamoxifen
---
https://minerva-ebp.be/fr/article/695
2006
false
false
minerva-ebm.be
Belgium
French
osteoporosis, postmenopausal
breast neoplasms
bone density conservation agents
estrogen antagonists
selective estrogen receptor modulators
fractures, bone
treatment outcome
Raloxifene Hydrochloride
critical appraisal or critical reading
---
https://www.cadth.ca/sites/default/files/pdf/117_raloxifene_tr_f.pdf
https://www.cadth.ca/fr/etude-methodique-de-lefficacite-et-de-linnocuite-du-raloxifene-dans-la-prevention-primaire-ou
2005
true
Canada
French
Raloxifene Hydrochloride
osteoporosis, postmenopausal
selective estrogen receptor modulators
fractures, bone
Raloxifene Hydrochloride
selective estrogen receptor modulators
treatment outcome
randomized controlled trials as topic
aged
canada
osteoporosis, postmenopausal
spinal fractures
bone density
osteoporosis, postmenopausal
signs and symptoms
risk factors
bibliography of medicine
incidence
placebos
fractures, bone
prevalence
thromboembolism
hot flashes
breast neoplasms
cardiovascular diseases
morbidity
bone density conservation agents
technical report
evaluation studies
french abstract
meta-analysis
---