selective estrogen receptor modulators

Preferred Label : selective estrogen receptor modulators;

MeSH definition : A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63);

MeSH synonym : serms; selective estrogen receptor modulator; estrogen receptor modulator, selective; estrogen receptor modulators, selective; serm;

MeSH annotation : do not confuse with ESTROGEN RECEPTOR MODULATORS;

Wikipedia link : https://en.wikipedia.org/wiki/Selective estrogen receptor modulator;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D020845;

UMLS CUI

C0732611;

ATC code(s)
- bazedoxifene [ATC Code]
- raloxifene [ATC Code]
- selective estrogen receptor modulators [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Product containing selective estrogen receptor modulator (product) [SNOMED CT concept]
- Selective estrogen receptor modulator (disposition) [SNOMED CT concept]
- Selective estrogen receptor modulator (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Selective Estrogen Receptor Modulator [NCIt concept]
- selective estrogen receptor modulators [ATC Code]
Indexing information
- 5-bromo-2-(4-chlorobenzoyl)-(Z)-3-(2-cyano-3-hydroxybut-2-enonyl)aminobenzo(b)furan [MeSH Supplementary Concept]
- BC-1 benzothiophene compound [MeSH Supplementary Concept]
- parthenocissin A [MeSH Supplementary Concept]
Ne pas confondre avec
- estrogen receptor modulators [MeSH Descriptor]
Record concept(s)
- selective estrogen receptor modulators [MeSH concept]
See also
- bone density conservation agents [MeSH Descriptor]
Semantic type(s)
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- LY 117018 [MeSH Supplementary Concept]
- Raloxifene Hydrochloride [MeSH Descriptor]
- afimoxifene [MeSH Supplementary Concept]
- bazedoxifene [MeSH Supplementary Concept]
- clomiphene [MeSH Descriptor]
- enclomiphene [MeSH Descriptor]
- oxabicycloheptene sulfonate [MeSH Supplementary Concept]
- tamoxifen [MeSH Descriptor]
- toremifene [MeSH Descriptor]
- zuclomiphene [MeSH Descriptor]
UMLS correspondences (same concept)
- Product containing selective estrogen receptor modulator (product) [SNOMED CT concept]
- Selective Estrogen Receptor Modulator [NCIt concept]
- Selective estrogen receptor modulator (substance) [SNOMED CT concept]
- selective estrogen receptor modulators [ATC Code]

Keyword's position in hierarchy(ies) :

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