LY 117018 - CISMeF

Preferred Label : LY 117018;

MeSH note : from Eli Lilly; less estrogenic & more estrogen-antagonistic than tamoxifen & trioxifene in rats & mice; LY 139478 is the HCl salt of LY 117018; LY 139478 is an estrogen agonist; structure in first source; a raloxifene analog;

CISMeF synonym : 6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl 4-(2-(1-pyrrolidinyl)ethoxy) phenyl ketone; LY 139478;

MeSH synonym : LY117018; Lilly 117018; LY-117018;

Related MeSH term : LY-139478;

MeSH CAS label : methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-;

Registry Number MeSH : 63676-25-5;

Is substance : O;

Details

Origin ID

C025430;

UMLS CUI

C0065279;

MeSH term(s) associated for indexing
- pyrrolidines [MeSH Descriptor]
- thiophenes [MeSH Descriptor]
Pharmacological action(s)
- estrogen antagonists [MeSH Descriptor]
- selective estrogen receptor modulators [MeSH Descriptor]
Record concept(s)
- 6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl 4-(2-(1-pyrrolidinyl)ethoxy) phenyl ketone [MeSH concept]
- LY 117018 [MeSH concept]
- LY 139478 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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