baclofen - CISMeF

Preferred Label : baclofen;

MeSH definition : A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.;

MeSH synonym : beta-(aminomethyl)-4-chlorobenzenepropanoic acid; beta-(p-chlorophenyl)-gamma-aminobutyric acid; pcp-gaba; chlorophenyl gaba; baclophen; gaba, chlorophenyl;

CISMeF synonym : ASTA medica brand of baclofen; Ciba-Geigy brand of baclofen; Nu-Pharm brand of baclofen; alphapharm brand of baclofen; apotex brand of baclofen; ashbourne brand of baclofen; athena brand of baclofen; baclofen Ciba-Geigy brand; baclofen Nu-Pharm brand; baclofen alphapharm brand; baclofen apotex brand; baclofen ashbourne brand; baclofen athena brand; baclofen irex brand; baclofen isis brand; baclofen medtronic brand; baclofen novartis brand; baclofen pharmascience brand; ciba geigy brand of baclofen; irex brand of baclofen; isis brand of baclofen; medtronic brand of baclofen; novartis brand of baclofen; nu pharm brand of baclofen; pharmascience brand of baclofen;

DeCS synonym : Lior sal; Baclof neIrex; Baclof ne Irex;

MeSH hyponym : liorésal; atrofen; Baclofène-Irex; lebic; lioresal; baclofen AWD; Apo-Baclofen; clofen; PMS-Baclofen; Gen-Baclofen; baclospas; Ba-34,647; Nu-Baclo; Gen Baclofen; GenBaclofen; Genpharm; Apo Baclofen; ApoBaclofen; Baclofène Irex; BaclofèneIrex; AWD, Baclofen; Nu Baclo; NuBaclo; PMS Baclofen; PMSBaclofen; Ba34,647; Ba-34647; Ba34647; CIBA-34,647-BA; CIBA34,647BA;

MeSH CAS label : benzenepropanoic acid, beta-(aminomethyl)-4-chloro-;

MeSH Related Number : 1134-47-0 (Baclofen);

Registry Number MeSH : 1134-47-0;

Wikipedia link : https://en.wikipedia.org/wiki/Baclofen;

Codes EINECS : 214-486-9;

Is substance : O;

UNII : H789N3FKE8;

InChIKey : KPYSYYIEGFHWSV-UHFFFAOYSA-N;

Details

Origin ID

D001418;

UMLS CUI

C0004609;

ATC code(s)
- baclofen [ATC Code]
ATC code(s)
- baclofen [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Baclofen, (S)- [NCIt concept]
CISMeF manual mappings
- Baclofen (substance) [SNOMED CT concept]
- Baclofen adverse reaction (disorder) [SNOMED CT concept]
- Baclofen measurement (procedure) [SNOMED CT concept]
- Baclofen overdose (disorder) [SNOMED CT concept]
- baclofen [Substance BNPC]
Pharmacological action(s)
- GABA agents [MeSH Descriptor]
- GABA-B receptor agonists [MeSH Descriptor]
- muscle relaxants, central [MeSH Descriptor]
Record concept(s)
- Apo-Baclofen [MeSH concept]
- Ba-34,647 [MeSH concept]
- Baclofène-Irex [MeSH concept]
- Gen-Baclofen [MeSH concept]
- Nu-Baclo [MeSH concept]
- PMS-Baclofen [MeSH concept]
- atrofen [MeSH concept]
- baclofen [MeSH concept]
- baclofen AWD [MeSH concept]
- baclospas [MeSH concept]
- clofen [MeSH concept]
- lebic [MeSH concept]
- lioresal [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-(4-chlorophenyl)-4-aminobutyric acid [MeSH Supplementary Concept]
- 2-amino-2-(4-chlorophenyl)ethanesulfonic acid [MeSH Supplementary Concept]
- 2-hydroxysaclofen [MeSH Supplementary Concept]
- 3-(4-chlorophenyl)-4-hydroxybutyric acid [MeSH Supplementary Concept]
- 5-amino-3-(4-chlophenyl)pentanoic acid [MeSH Supplementary Concept]
- 5-hydroxysaclofen [MeSH Supplementary Concept]
- CGP 11130 [MeSH Supplementary Concept]
- arbaclofen placarbil [MeSH Supplementary Concept]
- gamma-guanidinobaclofen [MeSH Supplementary Concept]
- phaclofen [MeSH Supplementary Concept]
- saclofen [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing baclofen (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Baclofen [ICD-11 Extension code]
- Baclofen [NCIt concept]
- Baclofen [LOINC component]
- Baclofen (substance) [SNOMED CT concept]
- Product containing baclofen (medicinal product) [SNOMED CT concept]
- baclofen [ATC Code]
- baclofen [Substance BNPC]
- baclofen [SNOMED Notion]
Validated automatic mappings to BTNT
- baclofen [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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