" /> Baclofen - CISMeF





Preferred Label : Baclofen;

NCIt synonyms : beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid; 4-Amino-3-(4-chlorophenyl)-butanoic Acid;

NCIt related terms : Kemstro; Lioresal;

NCIt definition : A synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors. It acts at spinal and supraspinal sites, reducing excitatory transmission. (NCI04);

Alternative definition : NCI-GLOSS: A drug that is used to treat certain types of muscle spasms and is being studied in the treatment of liver cancer. Baclofen relaxes muscles by blocking certain nerve receptors in the spinal cord. It is a type of antispasmodic.;

UNII : H789N3FKE8;

InChIKey : KPYSYYIEGFHWSV-UHFFFAOYSA-N;

CAS number : 1134-47-0;

Drug name : Lioresal; Kemstro; Gablofen;

Molecule name : BA34647;

Chemical formula : C10H12ClNO2;

NSC code : 329137;

ChEBI ID : CHEBI:2972;

Codes from synonyms : CDR0000593095; CDR0000593094; 00757; CDR0000561430;

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26/05/2025


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