Preferred Label : botulinum toxins, type A;
MeSH definition : A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED
PROTEIN 25.;
MeSH synonym : botulinum neurotoxin a; clostridium botulinum toxin type a; clostridium botulinum a toxin; botulinum a toxin; toxin, botulinum a; neurotoxin a, botulinum; botulinum toxin type A; Botulinum Toxin A; Toxin A, Botulinum; Botulinum Neurotoxin Type A;
CISMeF synonym : Neuronox;
MeSH hyponym : oculinum; meditoxin;
Related MeSH term : Onabotulinumtoxin A;
MeSH Related Number : E211KPY694;
Registry Number MeSH : EC 3.4.24.69;
MeSH annotation : /antag permitted but consider also BOTULINUM ANTITOXIN;
Wikipedia link : https://en.wikipedia.org/wiki/Oculinum;
Is substance : O;
UNII : EC 3.4.24.69;
Origin ID : D019274;
UMLS CUI : C0006050;
Allowable qualifiers
- Currated CISMeF NLP mapping
- Indexing information
- MedlinePlus topic(s)
- botox [MedlinePlus Topic]
- Ne pas confondre avec
- Pharmacological action(s)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- DWP450 [MeSH Supplementary Concept]
- coretox [MeSH Supplementary Concept]
- Semantic type(s)
- Validated automatic mappings to BTNT
- Validated automatic mappings to NTBT
A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED
PROTEIN 25.
https://www.has-sante.fr/jcms/p_3487172/fr/botox-toxine-botulinique-type-a-blepharospasme-spasme-hemifacial-torticolis-spasmodique
2024
false
false
false
France
treatment outcome
insurance, health, reimbursement
botulinum toxin
neuromuscular agents
evaluation of the transparency committee
hemifacial spasm
botulinum toxins, type A
blepharospasm
torticollis
Spasmodic Torticollis
---
https://ansm.sante.fr/actualites/decision-du-25-04-2024-cadre-de-prescription-compassionnelle-de-botox-50-100-et-200-unites-allergan-poudre-pour-solution-injectable
2024
false
false
false
France
French
botulinum toxins, type A
drug information
neuralgia
Chronic peripheral neuropathic pain (finding)
---
https://ansm.sante.fr/tableau-acces-derogatoire/botox
2024
false
false
false
France
French
guidelines for drug use
botulinum toxins, type A
neuralgia
chronic disease
adult
Chronic peripheral neuropathic pain (finding)
---
https://www.has-sante.fr/jcms/p_3434800/fr/dysport-500-unites-speywood-toxine-botulinique-type-a-blepharospasme-spasme-hemifacial-torticolis-spasmodique
2023
false
false
false
France
treatment outcome
insurance, health, reimbursement
adult
neuromuscular agents
botulinum toxin
evaluation of the transparency committee
torticollis
blepharospasm
hemifacial spasm
botulinum toxins, type A
---
https://www.has-sante.fr/jcms/p_3448222/fr/xeomin-neurotoxine-de-clostridium-botulinum-de-type-a-spasticite-des-membres-superieurs
2023
false
false
false
France
treatment outcome
insurance, health, reimbursement
botulinum toxin
neuromuscular agents
injections, intramuscular
Upper limb spasticity (finding)
adult
evaluation of the transparency committee
botulinum toxins, type A
upper extremity
muscle spasticity
---
https://www.has-sante.fr/jcms/p_3330893/fr/xeomin-toxine-botulinique-type-a-sialorrhee-chronique
2022
false
false
false
France
chronic disease
treatment outcome
insurance, health, reimbursement
nervous system diseases
Injection of therapeutic substance into salivary gland (procedure)
botulinum toxin
neuromuscular agents
evaluation of the transparency committee
botulinum toxins, type A
sialorrhea
---
https://www.has-sante.fr/jcms/p_3394941/fr/dysport-300-et-500-unites-speywood-toxine-botulinique-de-type-a-incontinence-urinaire
2022
false
false
false
France
insurance, health, reimbursement
treatment outcome
botulinum toxins, type A
urinary incontinence
neurogenic detrusor overactivity
Neurogenic detrusor overactivity (disorder)
spinal cord injuries
multiple sclerosis
botulinum toxin
neuromuscular agents
adult
injections, intramuscular
evaluation of the transparency committee
---
https://www.has-sante.fr/jcms/p_3303898/fr/botox-50-100-200-mg-toxine-botulinique-type-a-migraine-chronique
2021
false
false
false
France
migraine disorders
treatment outcome
insurance, health, reimbursement
Chronic Migraine
botulinum toxin
adult
injections, intramuscular
neuromuscular agents
chronic disease
evaluation of the transparency committee
botulinum toxins, type A
---
https://www.has-sante.fr/jcms/p_3202242/fr/dysport
2020
false
false
false
France
botulinum toxins, type A
botulinum toxin
insurance, health, reimbursement
child
treatment outcome
muscle spasticity
Upper limb spasticity
adolescent
neuromuscular agents
botulinum toxins, type A
neuromuscular agents
evaluation of the transparency committee
---
https://www.ema.europa.eu/en/medicines/human/EPAR/nuceiva
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
botulinum toxins, type A
botulinum toxins, type A
Glabellar frown lines
skin aging
adult
Acetylcholine Release Inhibitors
Acetylcholine Release Inhibitors
neuromuscular agents
neuromuscular agents
injections, intramuscular
product surveillance, postmarketing
pregnancy
breast feeding
botulinum toxin
Facial wrinkle removal (procedure)
---
https://www.has-sante.fr/jcms/p_3098271/fr/botox
2019
false
false
false
France
botulinum toxins, type A
botulinum toxin
multiple sclerosis
urinary bladder, overactive
urinary incontinence
treatment outcome
evaluation of the transparency committee
---
https://www.cochrane.org/fr/CD001408/injections-de-toxine-botulique-de-type-pour-le-traitement-de-la-spasticite-des-membres-inferieurs
2019
false
false
false
France
United Kingdom
botulinum toxins, type A
Lower limb spasticity (finding)
neuromuscular agents
injections, intramuscular
child
treatment outcome
review of literature
french abstract
lower extremity
cerebral palsy
muscle spasticity
---
https://www.has-sante.fr/jcms/c_2967154/fr/botox
2019
false
false
false
France
French
treatment outcome
evaluation of the transparency committee
adult
botulinum toxins, type A
botulinum toxin
urinary bladder, overactive
---
https://pharmacomedicale.org/medicaments/par-specialites/item/toxine-botulique
2017
false
true
false
France
botulinum toxins
botulinum toxins
botulinum toxins, type A
botulinum toxin
botulinum toxins
drug information
botulinum toxins
---
http://www.has-sante.fr/portail/jcms/c_2676759/fr/xeomin
2016
false
France
French
evaluation of the transparency committee
botulinum toxin
neuromuscular agents
blepharospasm
adult
torticollis
muscle spasticity
botulinum toxins, type A
injections, intramuscular
treatment outcome
upper extremity
clinical trials as topic
incobotulinumtoxinA
---
http://www.cochrane.org/fr/CD010750/les-traitements-medicamenteux-de-la-douleur-chez-les-enfants-et-les-jeunes-atteints-dune-maladie
2015
false
false
false
Switzerland
United Kingdom
French
pain
adolescent
child
french abstract
life expectancy
cerebral palsy
osteogenesis imperfecta
baclofen
botulinum toxins, type A
treatment outcome
diphosphonates
review of literature
---
http://www.rts.ch/emissions/36-9/7067823-ce-botox-qui-nous-veut-du-bien.html
2015
false
false
false
Switzerland
French
television programme
botulinum toxins, type A
---
http://www.has-sante.fr/portail/jcms/c_1782527/fr/botox
2014
false
France
French
urinary bladder, overactive
guidelines for drug use
evaluation of the transparency committee
neuromuscular agents
neuromuscular agents
botulinum toxins, type A
botulinum toxins, type A
botulinum toxin
adult
administration, intravesical
treatment outcome
insurance, health, reimbursement
comparative study
---
http://www.sciencedirect.com/science/article/pii/S1166708713007379
2013
false
false
false
France
French
practice guideline
consensus
botulinum toxins, type A
urinary bladder, overactive
administration, intravesical
neuromuscular agents
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67411667
2013
France
summary of product characteristics
botulinum toxins, type A
lethal dose 50
powders
multiprotein complexes
injections
---
http://www.sfdermato.org/media/pdf/information-patient/finfotbhidrose-757912730cfcbc9e45ef7e14c4ff426c.pdf
France
French
botulinum toxins, type A
hyperhidrosis
neuromuscular agents
patient education handout
---
http://www.sfdermato.org/media/pdf/information-patient/finfotbesthet-c4bb64bbf4d12d16ef8ff9c2641d29f9.pdf
France
French
botulinum toxins, type A
skin aging
face
neuromuscular agents
patient education handout
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68150775
2012
France
summary of product characteristics
package leaflet
powders
botulinum toxins, type A
injections
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61717276
2012
France
summary of product characteristics
package leaflet
powders
injections
botulinum toxins, type A
---
http://www.has-sante.fr/portail/jcms/c_1355068/dysport-toxine-botulinique-de-type-a
http://www.has-sante.fr/portail/jcms/c_1355067/dysport-synthese-ct12379
2012
France
French
evaluation of the transparency committee
guidelines for drug use
child
muscle spasticity
lower extremity
botulinum toxins, type A
AbobotulinumtoxinA
---
http://www.has-sante.fr/portail/jcms/c_1319594/injection-de-toxine-botulique-dans-la-musculeuse-vesicale-par-uretrocystoscopie-etude-sur-les-actes
http://www.has-sante.fr/portail/jcms/c_1323403/injection-de-toxine-botulique-dans-la-musculeuse-vesicale-par-uretrocystoscopie-etude-sur-les-actes
2012
France
French
assessment of professional actions
botulinum toxins, type A
injections
health technology assessment
urinary incontinence
cystoscopy
urinary bladder, overactive
treatment outcome
---
http://www.has-sante.fr/portail/jcms/c_1320029/botox-toxine-botulinique-de-type-a
http://www.has-sante.fr/portail/jcms/c_1319562/botox-18072012-synthese
http://www.has-sante.fr/portail/jcms/c_1282762/botox-18072012-avis-ct12193
2012
France
French
drug approval
overactive detrusor
urinary bladder, overactive
guidelines for drug use
evaluation of the transparency committee
neuromuscular agents
neuromuscular agents
botulinum toxins, type A
botulinum toxins, type A
botulinum toxin
adult
administration, intravesical
treatment outcome
insurance, health, reimbursement
injections, intramuscular
randomized controlled trials as topic
urinary incontinence
risk management
spinal cord injuries
multiple sclerosis
comparative study
---
http://www.has-sante.fr/portail/jcms/c_1294080/xeomin-synthese-23052012
http://www.has-sante.fr/portail/jcms/c_1257464/xeomin-23052012-avis-ct11992
http://www.has-sante.fr/portail/jcms/c_1294174/xeomin-50-u-toxine-botulique-de-type-a
2012
France
French
guidelines for drug use
evaluation of the transparency committee
botulinum toxin
neuromuscular agents
blepharospasm
adult
torticollis
muscle spasticity
botulinum toxins, type A
injections, intramuscular
treatment outcome
upper extremity
clinical trials as topic
incobotulinumtoxinA
---
http://www.has-sante.fr/portail/jcms/c_1281708/botox
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-08/botox_18072012_avis_ct12193.pdf
2012
France
French
evaluation of the transparency committee
botulinum toxins, type A
botulinum toxins, type A
neuromuscular agents
neuromuscular agents
botulinum toxin
adult
urinary bladder, overactive
overactive detrusor
spinal cord injuries
multiple sclerosis
injections, intramuscular
treatment outcome
risk management
product surveillance, postmarketing
comparative study
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-06/xeomin_23052012_avis_ct11992.pdf
http://www.has-sante.fr/portail/jcms/c_1256025/xeomin
2012
France
French
evaluation of the transparency committee
incobotulinumtoxinA
incobotulinumtoxinA
incobotulinumtoxinA
botulinum toxins, type A
botulinum toxins, type A
neuromuscular agents
neuromuscular agents
injections, intramuscular
treatment outcome
botulinum toxin
adult
blepharospasm
torticollis
muscle spasticity
stroke
randomized controlled trials as topic
comparative study
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-04/xeomin_-_ct_-_9626_2011-04-15_15-31-36_292.pdf
http://www.has-sante.fr/portail/jcms/c_1058980/xeomin-neurotoxine-de-clostridium-botulinum-de-type-a-myorelaxant
2011
France
French
guidelines for drug use
evaluation of the transparency committee
botulinum toxins, type A
neuromuscular agents
muscle spasticity
upper extremity
adult
stroke
botulinum toxin
injections, intramuscular
treatment outcome
incobotulinumtoxinA
---
http://www.cochrane.org/fr/CD003469
2010
United Kingdom
France
French
meta-analysis
botulinum toxins, type A
treatment outcome
cerebral palsy
occupational therapy
cerebral palsy
neuromuscular agents
french abstract
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-01/botox_-_ct-7305.pdf
http://www.has-sante.fr/portail/jcms/c_945955/botox-toxine-botulinique-de-type-a
2010
France
French
botulinum toxins, type A
child
muscle spasticity
botulinum toxin
treatment outcome
neuromuscular agents
injections, intramuscular
evaluation of the transparency committee
guidelines for drug use
---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2008/14572a-fra.php
2009
Canada
French
English
neurotoxins
neuromuscular agents
muscle weakness
pneumonia, aspiration
adult
child
botulinum toxins, type A
pharmacovigilance note
---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2008/13271a-fra.php
2008
Canada
French
English
neurotoxins
neuromuscular agents
botulinum toxins, type A
canada
pharmacovigilance note
---
http://www.has-sante.fr/portail/jcms/c_657773/xeomin
2008
France
French
neuromuscular agents
botulinum toxins, type A
adult
insurance, health, reimbursement
blepharospasm
torticollis
injections, intramuscular
botulinum toxin
incobotulinumtoxinA
evaluation of the transparency committee
---
https://medicalforum.ch/fr/detail/doi/fms.2007.06204/
2007
false
Switzerland
French
botulinum toxins, type A
muscle spasticity
neuromuscular agents
consensus
---
http://www.has-sante.fr/portail/display.jsp?id=c_520079
http://www.has-sante.fr/portail/display.jsp?id=c_520077
2006
France
French
hemifacial spasm
neuromuscular agents
blepharospasm
botulinum toxins, type A
assessment of professional actions
---
http://www.has-sante.fr/portail/display.jsp?id=c_520046
http://www.has-sante.fr/portail/display.jsp?id=c_520043
2006
France
French
axilla
treatment outcome
botulinum toxins, type A
neurotoxins
hyperhidrosis
botulinum toxins, type A
neurotoxins
neuromuscular agents
neuromuscular agents
assessment of professional actions
---
http://www.has-sante.fr/portail/display.jsp?id=c_520092
http://www.has-sante.fr/portail/display.jsp?id=c_520090
2006
France
French
strabismus
neuromuscular agents
child
botulinum toxins, type A
assessment of professional actions
---
https://www.cadth.ca/sites/default/files/pdf/172_BOTOX_tr_f.pdf
https://www.cadth.ca/fr/etude-methodique-de-la-toxine-botulinique-dans-la-spasticite-des-membres-superieurs-ou-des-membres
2005
true
Canada
French
botulinum toxins, type A
neuromuscular agents
muscle spasticity
upper extremity
lower extremity
injections, intramuscular
treatment outcome
botulinum toxins, type A
neuromuscular agents
randomized controlled trials as topic
canada
bibliography of medicine
range of motion, articular
muscle tonus
stroke
multiple sclerosis
cerebral palsy
muscle spasticity
pain
disability evaluation
gait
movement
dose-response relationship, drug
botulinum toxin
technical report
evaluation studies
french abstract
meta-analysis
drug evaluation
---
