Glucagon-Like Peptide 1

Preferred Label : Glucagon-Like Peptide 1;

NCIt synonyms : Incretin Hormone; GLP-1; GLP1; GCG;

NCIt definition : Glucagon-like peptide 1 (37 aa, 4 kDa) is encoded by the human GCG gene. This protein is involved in the stimulation of glucose-dependent insulin release.;

NCIt note : Glucagon-like peptide 1 is comprised of amino acids 92-128 of the full length proglucagon precursor protein. (UniProt);

NCI Metathesaurus CUI : CL1799054;

Details

Origin ID

C190208;

UMLS CUI

C5781577;

Automatic exact mappings (from CISMeF team)
- Glucagon [OMIM gene]
- glucagon [HGNC gene]
Currated CISMeF NLP mapping
- GLUCAGON-LIKE PEPTIDE 1 [SMS substance]
- Glucagon-Like peptide 1 [MeSH concept]
- Glucagon-like peptide 1 (substance) [SNOMED CT concept]
- glucagon like peptide 1 [Artificial nutrition thesaurus concept]
- glucagon-like peptide 1 [MeSH Descriptor]
- glucagon-like peptide 1 [SNOMED Notion]
OMIM relation
- Glucagon [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
gene_encodes_gene_product
- GCG Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_expressed_in_tissue
- Islet of Langerhans [NCIt concept]
gene_product_has_associated_anatomy
- Alpha Cell [NCIt concept]
- Endocrine Cell of the Digestive System [NCIt concept]
gene_product_is_element_in_pathway
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Gluconeogenic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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