thiazolidinediones

Preferred Label : thiazolidinediones;

MeSH definition : THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).;

MeSH synonym : glitazones;

CISMeF synonym : TZD;

Wikipedia automatic translation : Thiazolidinedione;

Wikipedia link : https://en.wikipedia.org/wiki/Thiazolidinedione;

Is substance : O;

Details

Origin ID

D045162;

UMLS CUI

C1257987;

ATC code(s)
- thiazolidinediones [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Thiazolidinedione Antidiabetic Agent [NCIt concept]
- Thiazolidinediones [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Thiazolidinedione (substance) [SNOMED CT concept]
Record concept(s)
- thiazolidinediones [MeSH concept]
Related MeSH Supplementary Concept(s)
- (2-(2-Phenoxy-1-(4-bromophenyl)ethylidene)hydrazono)-5-ethylthiazolidin-4-one [MeSH Supplementary Concept]
- (Z)-2-chloro-5-(5-((4-oxo-3-phenethyl-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid [MeSH Supplementary Concept]
- (Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- (Z)2-(5-(4-methoxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetic acid [MeSH Supplementary Concept]
- 1,13a-dihydro-3H,5H,13H-naphtho(2,3-f)thiazolo(4,3-c)(1,4)thiazepine-5,13-dione [MeSH Supplementary Concept]
- 1,2,4-dithiazolidine-3,5-dione [MeSH Supplementary Concept]
- 2,3-dihydro-5H-naphtho(2,3-f)thiazolo(2,3-c)(1,4)thiazepine-5,13(1aH)-dione [MeSH Supplementary Concept]
- 2,4-thiazolidinedione [MeSH Supplementary Concept]
- 2-(3-((4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenylamino)methyl)benzamido)pentanedioic acid [MeSH Supplementary Concept]
- 3-((3-((4-(4-morpholinylmethyl)-1H-pyrrol-2-yl)methylene)-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl)-1,3-thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 3-(2-aminoethyl)-5-(3-(4-butoxylphenyl)propylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 3-(3,4-dichlorobenzyl)-5-(3,4,5-trihydroxybenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione [MeSH Supplementary Concept]
- 3-benzyl-2-(4-fluorophenyl)-1,3-thiazolidin-4-one [MeSH Supplementary Concept]
- 3-benzyl-5-(1H-indol-3-ylmethylene)-thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 3-benzyl-5-acridinylidene-thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 3-tert-butoxycarbonylmethyl-5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 4-((5-bromo-4-((2,4-dioxo-3-(2-oxo-2-phenylethyl)-1,3-thiazolidin-5-ylidene)methyl)-2-ethoxyphenoxy)methyl)benzoic acid [MeSH Supplementary Concept]
- 4-(4-(2,4-dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy)-3-trifluoromethylbenzonitrile [MeSH Supplementary Concept]
- 4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione [MeSH Supplementary Concept]
- 5-((2-(2-naphthalenylmethyl)-5-benzoxazolyl)methyl)-2,4-thiazolidinedione [MeSH Supplementary Concept]
- 5-((4-(2-(1-indolyl)ethoxy)-phenyl)methyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-((4-(2-(5-methyl-2-phenyl-oxazol-4-yl)ethoxy)benzo(2) thiophen-7-yl)methyl)-thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-((5-bromo-1H-indol-3-yl)methylene)-3-(4-chlorobenzyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(2,2-difluorobenzo(1,3)dioxol-5-ylmethylene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(2-chloro-3-(3-phenylpropoxy)benzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(2-naphthalenylsulfonyl)-2,4-thiazolidinedione [MeSH Supplementary Concept]
- 5-(3,5-di-tert-butyl-4-hydroxybenzyl)-4-hydroxythiazol-2(5H)-one [MeSH Supplementary Concept]
- 5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(3-(3-(4-phenoxy-2-propylphenoxy)propoxy)phenyl)-2,4-thiazolidinedione [MeSH Supplementary Concept]
- 5-(3-methoxyphenylidene)-2-phenylimino-3-propyl-4-thiazolidinone [MeSH Supplementary Concept]
- 5-(3-trifluoromethylbenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-((1-(pyridin-2-yl)pyrrolidin-2-yl)methoxy)phenylmethylene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-(2-(2-ethyl-4-methyl-6-oxo-1,6-dihydro-1-pyrimidinyl)ethoxy)phenylmethyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-(5-methoxy-3-methyl-3H-imidazo(4,5-b)pyridin-2-ylmethoxy)benzyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)-2,4-dioxothiazollidine, troglitazone dihydrate [MeSH Supplementary Concept]
- 5-(4-(N-(2-pyridyl)-(2S)-pyrrolidine-2-methoxy)phenylmethylene) thiazolidine-2,6-dione [MeSH Supplementary Concept]
- 5-(4-(cyclohexylethoxy)benzylidene)-2,4-thiazolidinedione [MeSH Supplementary Concept]
- 5-(4-(cyclopentylmethoxy)benzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-bromobenzylidene)-alpha-isopropyl-4-oxo-2-thioxo-3-thazolidineacetic acid [MeSH Supplementary Concept]
- 5-(4-chlorobenzylidene)-3-(4-methylbenzyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-hydroxy-3,5-dimethylbenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-hydroxy-3-trifluoromethylbenzylidene)-3-(1-methylcyclohexyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-hydroxy-3-trifluoromethylbenzylidene)-3-(4,4,4-trifluoro-2-methyl-2-(2,2,2-trifluoroethyl)butyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(4-methoxybenzylidene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(5-(4-fluoro-2-hydroxyphenyl)furan-2-ylmethylene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(5-bromo-2-methoxybenzylidene)-3-(4-methyl-benzyl)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-acridin-9-ylmethylene-3-(4-methyl-benzyl)-thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-adamantylpentanoic acid (2-(4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxy)ethyl)(methyl)amide [MeSH Supplementary Concept]
- 5-benzylidene thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-benzylidene-3-(4-methyl-benzyl)-thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-carboxymethyl-3-p-tolylthiazolidine-2,4-dione-2-acetophenone [MeSH Supplementary Concept]
- 5-hydroxypioglitazone [MeSH Supplementary Concept]
- 5-hydroxyrosiglitazone [MeSH Supplementary Concept]
- 5-quinoxalin-6-ylmethylenethiazolidine-2,4-dione [MeSH Supplementary Concept]
- AD 5075 [MeSH Supplementary Concept]
- ADD 4743 [MeSH Supplementary Concept]
- AL 321 [MeSH Supplementary Concept]
- BFF-816 [MeSH Supplementary Concept]
- BLX 1002 [MeSH Supplementary Concept]
- BM 131246 [MeSH Supplementary Concept]
- BM 501050 [MeSH Supplementary Concept]
- CAY10415 [MeSH Supplementary Concept]
- CAY10506 [MeSH Supplementary Concept]
- DN 108 [MeSH Supplementary Concept]
- DRF 2519 [MeSH Supplementary Concept]
- FX1 thiazolidinedione compound [MeSH Supplementary Concept]
- GQ-177 [MeSH Supplementary Concept]
- M-II compound [MeSH Supplementary Concept]
- M-IV compound [MeSH Supplementary Concept]
- MK-2305 [MeSH Supplementary Concept]
- MSDC-0160 [MeSH Supplementary Concept]
- MSDC-0602 [MeSH Supplementary Concept]
- N-((4-(biphenyl-2-ylmethoxy)-1-(2-(4-fluorobenzoyl)benzoyl)pyrrolidin-2-yl)methyl)-4-((2,4-dioxothiazolidin-5-ylidene)methyl)benzamide [MeSH Supplementary Concept]
- N-(-4-(N-(biphenyl-2-ylmethyl)-N-2-methylpropylamino)- 1-(2-(2,4-difluorobenzoyl)benzoyl)pyrrolidin- 2-yl)methyl-3-(4-(2,4-dioxothiazolidin-5-ylidenemethyl) phenyl)acrylamide [MeSH Supplementary Concept]
- N-(2-(4-((2,4-dioxo-1,3-thiazolidin-5-yl)methyl)phenoxy)ethyl)-5-(1,2-dithiolan-3-yl)-N-methylpentanamide [MeSH Supplementary Concept]
- N-(3-chlorophenyl)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetamide [MeSH Supplementary Concept]
- N-(4-(3-(1-methyl-cyclohexylmethyl)-2,4-dioxothiazolidin-5-ylidenemethyl)phenyl)-4-nitro-3-trifluoromethylbenzenesulfonamide [MeSH Supplementary Concept]
- N-desmethylrosiglitazone [MeSH Supplementary Concept]
- NIP-222 [MeSH Supplementary Concept]
- OSU-53 [MeSH Supplementary Concept]
- OSU-CG5 [MeSH Supplementary Concept]
- R 147176 [MeSH Supplementary Concept]
- SB-271258 [MeSH Supplementary Concept]
- SMI-4a compound [MeSH Supplementary Concept]
- TD49 thiazolidinedione [MeSH Supplementary Concept]
- ZINC17167211 [MeSH Supplementary Concept]
- balaglitazone [MeSH Supplementary Concept]
- chromonyl-2,4-thiazolidinedione [MeSH Supplementary Concept]
- ciglitazone [MeSH Supplementary Concept]
- darglitazone [MeSH Supplementary Concept]
- efatutazone [MeSH Supplementary Concept]
- englitazone [MeSH Supplementary Concept]
- iCRT14 [MeSH Supplementary Concept]
- iCTR14 compound [MeSH Supplementary Concept]
- leriglitazone [MeSH Supplementary Concept]
- lobeglitazone [MeSH Supplementary Concept]
- netoglitazone [MeSH Supplementary Concept]
- risarestat [MeSH Supplementary Concept]
- rivoglitazone [MeSH Supplementary Concept]
- thiazolidine-2,4-dione [MeSH Supplementary Concept]
- thiazolidine-2,4-thione [MeSH Supplementary Concept]
- thiazolidinedione-8 [MeSH Supplementary Concept]
- troglitazone sulfate [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing thiazolidinedione (product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing thiazolidinedione (product) [SNOMED CT concept]
- Thiazolidinedione (substance) [SNOMED CT concept]
Validated automatic mappings to BTNT
- 2,4-thiazolidinedione [Substance BNPC]
- thiazolidinediones [ATC Code]

Keyword's position in hierarchy(ies) :

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