Exenatide - CISMeF

Preferred Label : Exenatide;

MeSH definition : A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the Gila monster lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used an anti-diabetic and anti-obesity agent.; A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the GILA MONSTER lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used as an anti-diabetic and anti-obesity agent.;

MeSH Hyperonym : Ex4 Peptide; Peptide, Ex4; Exendin 4;

MeSH Related Number : 141732-76-5 (Exenatide);

UNII : 9P1872D4OL;

InChIKey : HTQBXNHDCUEHJF-XWLPCZSASA-N;

Details

Origin ID

D000077270;

UMLS CUI

C0167117;

ATC code(s)
- exenatide [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
MeSH indexing information
- glucagon-like peptide 1 [MeSH Descriptor]
- lizards [MeSH Descriptor]
- venoms [MeSH Descriptor]
Pharmacological action(s)
- anti-obesity agents [MeSH Descriptor]
- hypoglycemic agents [MeSH Descriptor]
- incretins [MeSH Descriptor]
Record concept(s)
- AC 2993 [MeSH concept]
- AC 2993 LAR [MeSH concept]
- Exendin-4 [MeSH concept]
- ITCA 650 [MeSH concept]
- bydureon [MeSH concept]
- byetta [MeSH concept]
- exenatide [MeSH concept]
See also inter- (CISMeF)
- Product containing exenatide (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- exenatide [ATC Code]

Keyword's position in hierarchy(ies) :

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