dipeptidyl-peptidase iv inhibitors

Preferred Label : dipeptidyl-peptidase iv inhibitors;

MeSH definition : Compounds that suppress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release.;

MeSH synonym : gliptins; Dipeptidyl-Peptidase 4 inhibitors; dipeptidyl peptidase 4 inhibitors; dipeptidyl peptidase IV inhibitors; DPP-4 Inhibitor; DPP 4 Inhibitor; Inhibitor, DPP-4; DPP-IV Inhibitor; DPP IV Inhibitor; Inhibitor, DPP-IV; DPP-4 Inhibitors; DPP 4 Inhibitors; DPP-IV Inhibitors; DPP IV Inhibitors; Gliptin; Dipeptidyl Peptidase 4 Inhibitor; Dipeptidyl-Peptidase IV Inhibitor; Dipeptidyl Peptidase IV Inhibitor; Inhibitor, Dipeptidyl-Peptidase IV; Dipeptidyl-Peptidase 4 Inhibitor; Inhibitor, Dipeptidyl-Peptidase 4; DPP4 Inhibitor; Inhibitor, DPP4; DPP4 Inhibitors;

CISMeF synonym : inhibitors, dipeptidyl-peptidase iv;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D054873;

UMLS CUI

C1827106;

ATC code(s)
- dipeptidyl peptidase 4 (DPP-4) inhibitors [ATC Code]
- linagliptin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Dipeptidyl peptidase 4 inhibitors [ICD-11 Extension code]
- Dipeptidyl peptidase IV inhibitor (disposition) [SNOMED CT concept]
- dipeptidyl peptidase 4 (DPP-4) inhibitors [ATC Code]
CISMeF manual mappings
- Substance with dipeptidyl peptidase IV inhibitor mechanism of action (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Dipeptidyl Peptidase-4 Inhibitor [NCIt concept]
Indexing information
- 1-((2-adamantyl)amino)acetyl-2-cyano-(S)-pyrrolidine, monohydrochloride [MeSH Supplementary Concept]
- 1-(5-((3,3-difluoropyrrolidin-1-yl)carbonyl)pyrrolidin-3-yl)-4-(4-fluoro-3-methylphenyl)-1H-1,2,3-triazole [MeSH Supplementary Concept]
- 1-(5-((3,3-difluoropyrrolidin-1-yl)carbonyl)pyrrolidin-3-yl)-4-(4-phenylphenyl)-1H-1,2,3-triazole [MeSH Supplementary Concept]
- 2-((2-(4-aminopiperidin-1-yl)-2-oxoethyl)sulfanyl)-4-hydroxy-6-phenylpyrimidine-5-carbonitrile [MeSH Supplementary Concept]
- 2-((3-(aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinolin-6-yl)oxy)acetamide [MeSH Supplementary Concept]
- 2-((6-(3-amino-3-methylpiperidine-1-yl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo(3,2-d)pyrimidine-5-yl)methyl)-4-fluorobenzonitrile [MeSH Supplementary Concept]
- 2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)-2,6-dihydropyrrolo(3,4-c)pyrazol-5(4H)-yl)tetrahydro-2H-pyran-3-amine [MeSH Supplementary Concept]
- 2-(2-(4-(4-chlorophenyl)piperazin-1-yl)-2-oxoethylsulfanyl)-4-hydroxy-6-phenyl-pyrimidine-5-carbonitrile [MeSH Supplementary Concept]
- 2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo(3,4-b)pyridin-6(7H)-yl)-N,N-dimethylacetamide [MeSH Supplementary Concept]
- 3-(4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-ylcarbonyl)thiazolidine [MeSH Supplementary Concept]
- 4-hydroxy-2-((2-oxo-2-(4-(pyridin-2-yl)piperazin-1-yl)ethyl)sulfanyl)-6-phenylpyrimidine-5-carbonitrile [MeSH Supplementary Concept]
- 5-(2-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)propyl)-5-(1H-tetrazol-5-yl)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene-2,8-dicarboxylic acid bisdimethylamide [MeSH Supplementary Concept]
- 5-(aminomethyl)-6-(2,2-dimethylpropyl)-2-ethyl-4-(4-methylphenyl)pyridin-3-ylacetic acid [MeSH Supplementary Concept]
- 8-(3-amino-1-piperidinyl)-7-(2-butyn-1-yl)-1-((4,6-dimethyl-2-pyrimidinyl)methyl)-3-methylxanthine [MeSH Supplementary Concept]
- KR 66223 [MeSH Supplementary Concept]
- MK0626 [MeSH Supplementary Concept]
- NWT-03 [MeSH Supplementary Concept]
- anagliptin [MeSH Supplementary Concept]
- gosogliptin [MeSH Supplementary Concept]
- methyl 1-(5-((3,3-difluoropyrrolidin-1-yl)carbonyl)pyrrolidin-3-yl)-1H-1,2,3-triazole-4-carboxylate [MeSH Supplementary Concept]
MeSH Descriptor(s) used for indexing
- dipeptidyl peptidase 4 [MeSH Descriptor]
Metaterm(s)
- endocrinology [CISMeF Metaterm]
Record concept(s)
- Dipeptidyl-Peptidase IV inhibitors [MeSH concept]
See also (suggested by CISMeF)
- incretins [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing dipeptidyl peptidase IV inhibitor (product) [SNOMED CT concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- (3,3-difluoropyrrolidin-1-yl)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl)methanone [MeSH Supplementary Concept]
- 1-(((1-(hydroxymethyl)cyclopentyl)amino)acetyl)pyrrolidine-2,5-dicarbonitrile [MeSH Supplementary Concept]
- 1-(((2-((5-cyanopyridin-2-yl)amino)ethyl)amino)acetyl)-2-cyano-(S)-pyrrolidine [MeSH Supplementary Concept]
- 1-((6-hydroxy-2-azabicyclo(2.2.1)hept-3-yl)carbonyl)-2-pyrrolidinecarbonitrile [MeSH Supplementary Concept]
- 1-(2'-amino-3',3'-dimethylbutanoyl)pyrrolidine-2-carbonitrile [MeSH Supplementary Concept]
- 1-(2-(5-cyano-2-pyridinylamino)ethylamino)acetyl-2-pyrrolidinecarbonitrile [MeSH Supplementary Concept]
- 1-(4-aminomethyl-4-(3-chlorophenyl)cyclohexyl)-tetrahydropyrimidin-2-one [MeSH Supplementary Concept]
- 3-amino-1-(1-boronic-ethyl)pyrrolidine-2-one [MeSH Supplementary Concept]
- 3-amino-4-(2,4,5-trifluorophenyl)-N-(4-(6-(2-methoxyethoxy)benzothiazol-2-yl)tetrahydropyran-4-yl)butanamide [MeSH Supplementary Concept]
- 3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-(1,2,4)triazolo(1,5-a)pyridin-6-ylphenyl)butanamide [MeSH Supplementary Concept]
- 4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one [MeSH Supplementary Concept]
- 4-(8-(4-fluorobenzyl)-3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-amine [MeSH Supplementary Concept]
- 4-(8-methyl-3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-amine [MeSH Supplementary Concept]
- 5-hydroxysaxagliptin [MeSH Supplementary Concept]
- ABT 341 [MeSH Supplementary Concept]
- Linagliptin [MeSH Descriptor]
- N-alanylproline-O-(4-nitrobenzoyl)hydroxylamine [MeSH Supplementary Concept]
- NN 7201 [MeSH Supplementary Concept]
- Sitagliptin Phosphate [MeSH Descriptor]
- TMC 2B [MeSH Supplementary Concept]
- TMC 2C [MeSH Supplementary Concept]
- Vildagliptin [MeSH Descriptor]
- alogliptin [MeSH Supplementary Concept]
- anagliptin [MeSH Supplementary Concept]
- diprotin A [MeSH Supplementary Concept]
- lipoyl vildagliptin [MeSH Supplementary Concept]
- methionyl-2-cyanopyrrolidine [MeSH Supplementary Concept]
- saxagliptin [MeSH Supplementary Concept]
- sulphostin [MeSH Supplementary Concept]
- syrrx 106124 [MeSH Supplementary Concept]
UMLS correspondences (same concept)
- Product containing dipeptidyl peptidase IV inhibitor (product) [SNOMED CT concept]
- Substance with dipeptidyl peptidase IV inhibitor mechanism of action (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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