dipeptidyl peptidase 4

Preferred Label : dipeptidyl peptidase 4;

MeSH definition : A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.;

MeSH synonym : antigen, cd26; cd26 antigens; adenosine deaminase complexing protein 2; Dipeptidyl-Peptidase IV; dipeptidyl peptidase iv; cd26 antigen; antigens, CD26;

CISMeF synonym : adenosine deaminase-binding proteins; adenosine deaminase binding proteins;

Registry Number MeSH : EC 3.4.14.5;

Is substance : O;

UNII : EC 3.4.14.5;

Details

Origin ID

D018819;

UMLS CUI

C0081937;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Dipeptidyl Peptidase 4 [NCIt concept]
- Dipeptidyl peptidase IV (substance) [SNOMED CT concept]
- dipeptidyl peptidase iv [SNOMED Notion]
Indexing information
- 1-(2-(5-cyano-2-pyridinylamino)ethylamino)acetyl-2-pyrrolidinecarbonitrile [MeSH Supplementary Concept]
- 1-(4-aminomethyl-4-(3-chlorophenyl)cyclohexyl)-tetrahydropyrimidin-2-one [MeSH Supplementary Concept]
- 4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazin-2-one [MeSH Supplementary Concept]
- 6-(aminomethyl)-5-(2,4-dichlorophenyl)-N-(1-ethyl-1H-pyrazol-5-yl)-7-methylimidazo(1,2-a)pyrimidine-2-carboxamide [MeSH Supplementary Concept]
- KR 66222 [MeSH Supplementary Concept]
- P32-98 compound [MeSH Supplementary Concept]
- atrn protein, mouse [MeSH Supplementary Concept]
- atrn protein, rat [MeSH Supplementary Concept]
- carmegliptin [MeSH Supplementary Concept]
- glycyl-prolyl-diphenylphosphonic acid [MeSH Supplementary Concept]
- lipoyl vildagliptin [MeSH Supplementary Concept]
Record concept(s)
- dipeptidyl peptidase 4 [MeSH concept]
Related MeSH Supplementary Concept(s)
- DPP4 protein, human [MeSH Supplementary Concept]
- DPP4 protein, rat [MeSH Supplementary Concept]
- Dpp4 protein, mouse [MeSH Supplementary Concept]
- api m 5 allergen, apis mellifera [MeSH Supplementary Concept]
- ome protein, Drosophila [MeSH Supplementary Concept]
- ves v 3 allergen, vespula vulgaris [MeSH Supplementary Concept]
Related MeSH term(s)
- dipeptidyl-peptidase iv inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Adenosine deaminase binding protein [LOINC component]
- CD26 [LOINC component]
- Dipeptidyl peptidase IV (substance) [SNOMED CT concept]
- adenosine deaminase binding protein [SNOMED Notion]
- dipeptidyl peptidase iv [SNOMED Notion]
- lymphocyte antigen cd26 [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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