immunoglobulin fc fragments

Preferred Label : immunoglobulin fc fragments;

MeSH definition : Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.;

MeSH synonym : immunoglobulins, fc fragment; fc fragment, immunoglobulin; fc immunoglobulins; fc fragments; immunoglobulins, fc; fragment immunoglobulins, fc; immunoglobulin fc fragment; fc fragments, immunoglobulin; fc fragment immunoglobulins; Ig Fc Fragments; Fc Fragments, Ig; Fragments, Ig Fc; Fc Fragment; Fragment, Fc; Fc Immunoglobulin; Immunoglobulin, Fc;

MeSH annotation : DF: IG FC;

Is substance : O;

Details

Origin ID

D007141;

UMLS CUI

C0021032;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Fc fragment [LOINC component]
- Immunoglobulin Fc [NCIt concept]
- Immunoglobulin, Fc fragment (substance) [SNOMED CT concept]
- Immunoglobulin, Fc' fragment (substance) [SNOMED CT concept]
- immunoglobulin, fc fragment [SNOMED Notion]
- immunoglobulin, fc' fragment [SNOMED Notion]
- membrane spanning 4-domains A2 [HGNC gene]
Indexing information
- SHPS-1-Fc fusion protein [MeSH Supplementary Concept]
- gm(m) [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- immunoglobulin fc fragments [MeSH concept]
Related MeSH Supplementary Concept(s)
- ALK1-Fc fusion protein, human [MeSH Supplementary Concept]
- ALX148 [MeSH Supplementary Concept]
- AMG 745 [MeSH Supplementary Concept]
- BF02 protein [MeSH Supplementary Concept]
- BI 836858 [MeSH Supplementary Concept]
- FS102 antibody fragment [MeSH Supplementary Concept]
- Fc-EDA [MeSH Supplementary Concept]
- GC1113 [MeSH Supplementary Concept]
- HB-002.1 fusion protein [MeSH Supplementary Concept]
- IBI302 [MeSH Supplementary Concept]
- IL-13 receptor alpha2-Fc fusion protein, canis familiaris [MeSH Supplementary Concept]
- LAPS-FSH peptide [MeSH Supplementary Concept]
- OMP-54F28 [MeSH Supplementary Concept]
- OPG-Fc fusion protein, rat [MeSH Supplementary Concept]
- RCT-18 fusion protein [MeSH Supplementary Concept]
- T0001 [MeSH Supplementary Concept]
- TEM8-Fc [MeSH Supplementary Concept]
- alpha-1-anti-trypsin-IgG1 Fc fusion protein [MeSH Supplementary Concept]
- anbainuo protein, human [MeSH Supplementary Concept]
- aspartyl-seryl-aspartyl-glycyl-lysine [MeSH Supplementary Concept]
- dulaglutide [MeSH Supplementary Concept]
- eflapegrastim [MeSH Supplementary Concept]
- ephrin A1-Fc fusion protein, recombinant [MeSH Supplementary Concept]
- factor IX Fc fusion protein [MeSH Supplementary Concept]
- factor VIII-Fc fusion protein [MeSH Supplementary Concept]
- immunoglobulin facb fragment [MeSH Supplementary Concept]
- interferon beta-1a-Fc fusion protein [MeSH Supplementary Concept]
- luspatercept [MeSH Supplementary Concept]
- revacept [MeSH Supplementary Concept]
See also
- receptors, fc [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Fc fragment [LOINC component]
- Immunoglobulin Fc [NCIt concept]
- Immunoglobulin, Fc fragment (substance) [SNOMED CT concept]
- immunoglobulin, fc fragment [SNOMED Notion]

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