Preferred Label : receptors, aryl hydrocarbon;
MeSH definition : Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus,
and activate transcription of particular DNA segments. AH receptors are identified
by their high-affinity binding to several carcinogenic or teratogenic environmental
chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and
smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including
dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but
an unknown natural messenger with a role in cell differentiation and development is
suspected.;
MeSH synonym : aryl hydrocarbon receptor; dioxin receptor; polyaromatic hydrocarbon receptor; tcdd receptors; polyaromatic hydrocarbon receptors; receptor, ah; receptor, aryl hydrocarbon; receptor, dioxin; receptor, polyaromatic hydrocarbon; receptor, tcdd; receptors, ah; receptors, dioxin; receptors, polyaromatic hydrocarbon; receptors, tcdd; receptors, 2,3,7,8-tetrachlorodibenzo-p-dioxin; tcdd receptor; aryl hydrocarbon receptors; dioxin receptors; ah receptor; ah receptors;
MeSH annotation : DF: RECEPT AH;
Wikipedia link : https://en.wikipedia.org/wiki/Receptors, aryl hydrocarbon;
Is substance : O;
Origin ID : D018336;
UMLS CUI : C0052441;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- False automatic mappings
- Indexing information
- SGA 360 [MeSH Supplementary Concept]
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus,
and activate transcription of particular DNA segments. AH receptors are identified
by their high-affinity binding to several carcinogenic or teratogenic environmental
chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and
smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including
dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but
an unknown natural messenger with a role in cell differentiation and development is
suspected.
