Zinc Transporter 8

Preferred Label : Zinc Transporter 8;

NCIt synonyms : ZNT8; SLC30A8; Solute Carrier Family 30 Member 8; ZnT-8;

NCIt definition : Zinc transporter 8 (369 aa, 41 kDa) is encoded by the human SLC30A8 gene. This protein plays a role in zinc-efflux transporter activity.;

Alternative definition : CDISC: An islet beta-cell secretory membrane protein encoded by the SLC30A8 gene and regulates biosynthesis and secretion of insulin. It can be considered as an autoantigen and is commonly associated with the autoimmune disease type 1 diabetes mellitus.;

Details

Origin ID

C175415;

UMLS CUI

C1527996;

Automatic exact mappings (from CISMeF team)
- Solute carrier family 30 (zinc transporter), member 8 [OMIM gene]
- Zinc Transporter 8 [MeSH Descriptor]
- Zinc Transporter 8 [MeSH concept]
- Zinc transporter 8 [LOINC component]
- solute carrier family 30 member 10 [ORDO Gene]
- solute carrier family 30 member 10 [HGNC gene]
- solute carrier family 30 member 8 [HGNC gene]
OMIM relation
- Solute carrier family 30 (zinc transporter), member 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC30A8 protein, human [MeSH Supplementary Concept]
- SLC30A8 protein, human [MeSH concept]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC30A8 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Secretory Vesicle [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chelating Activity [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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