Zinc Transporter 8

Preferred Label : Zinc Transporter 8;

MeSH definition : A zinc efflux transporter highly expressed by ISLET CELLS of the pancreas. It functions in the accumulation of zinc in intracellular vesicles and may be involved in INSULIN maturation and storage processes. Variations in the SLC30A8 gene are associated with susceptibility to DIABETES MELLITUS, TYPE 2.;

MeSH synonym : ZnT-8 Protein; ZnT 8 Protein; Slc30A8 Protein; Solute Carrier Family 30 Member 8 Protein;

Details

Origin ID

D000075703;

UMLS CUI

C4019440;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- SLC30A8 wt Allele [NCIt concept]
- Solute carrier family 30 (zinc transporter), member 8 [OMIM gene]
- Zinc Transporter 8 [NCIt concept]
- Zinc transporter 8 [LOINC component]
- solute carrier family 30 member 10 [ORDO Gene]
- solute carrier family 30 member 10 [HGNC gene]
- solute carrier family 30 member 8 [HGNC gene]
Record concept(s)
- Zinc Transporter 8 [MeSH concept]
Related MeSH Supplementary Concept(s)
- SLC30A8 protein, human [MeSH Supplementary Concept]
- Slc30a8 protein, mouse [MeSH Supplementary Concept]
- Slc30a8 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- Zinc transporter 8 [LOINC component]

Keyword's position in hierarchy(ies) :

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