Run Domain Beclin-1-Interacting and Cysteine-Rich Domain-Containing Protein

Preferred Label : Run Domain Beclin-1-Interacting and Cysteine-Rich Domain-Containing Protein;

NCIt synonyms : Baron; Rubicon; RUN and Cysteine Rich Domain Containing Beclin 1 Interacting Protein; RUN Domain- and Cysteine-Rich Domain-Containing, Beclin-1-Interacting Protein; Rundataxin; RUN Domain and Cysteine-Rich Domain Containing, Beclin 1-Interacting Protein; Beclin-1 Associated RUN Domain Containing Protein; RUBCN;

NCIt definition : Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (972 aa, 109 kDa) is encoded by the human RUBCN gene. This protein plays a role in the negative regulation of phosphatidylinositol 3-kinase complex II activity, endocytosis and autophagy.;

Details

Origin ID

C170836;

UMLS CUI

C5400893;

OMIM relation
- Run domain- and cysteine-rich domain-containing beclin-1-interacting protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- RUBCN Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Endosome [NCIt concept]
- Lysosome [NCIt concept]
gene_product_has_chemical_classification
- Phosphoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Antimicrobial Effect [NCIt concept]
- Autophagy [NCIt concept]
- Endocytosis Inhibition [NCIt concept]
- Ligand Binding [NCIt concept]
- Phagocytosis Inhibition [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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