NKG2-A/NKG2-B Type II Integral Membrane Protein

Preferred Label : NKG2-A/NKG2-B Type II Integral Membrane Protein;

NCIt synonyms : NKG2-1/B Activating NK Receptor; CD159a; KLRC1; Natural Killer Cell Lectin; Natural Killer Group Protein 2; CD159a Antigen; NKG2-A/B Type II Integral Membrane Protein; NK Cell Receptor A; CD159 Antigen-Like Family Member A; C-Lectin Type II Protein; NKG2-A/B-Activating NK Receptor;

NCIt definition : NKG2-A/NKG2-B type II integral membrane protein (233 aa, 26 kDa) is encoded by the human KLRC1 gene. This protein is involved in the modulation of cell-mediated immunity.;

Details

Origin ID

C104364;

UMLS CUI

C3538762;

Automatic exact mappings (from CISMeF team)
- Killer cell lectin-like receptor, subfamily C, member 1 [OMIM gene]
- NK cell Lectin-Like receptor subfamily C [MeSH Descriptor]
- killer cell lectin like receptor C1 [HGNC gene]
- receptors, natural killer cell [MeSH Descriptor]
OMIM relation
- Killer cell lectin-like receptor, subfamily C, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- KLRC1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
- Natural Killer Cell [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Immunoprotein [NCIt concept]
- Lectin [NCIt concept]
gene_product_has_chemical_classification
- CD159 Family [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Antigen Processing and Presentation Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Ras-Independent Cell-Mediated Cytotoxicity Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-NKG2A Monoclonal Antibody Sym025 [NCIt concept]

Keyword's position in hierarchy(ies) :

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