Neuromedin-B Receptor

Preferred Label : Neuromedin-B Receptor;

NCIt synonyms : NMBR; Neuromedin B Receptor; Epididymis Tissue Protein Li 185a; Bombesin Receptor 1; Neuromedin-B-Preferring Bombesin Receptor; NMB-R;

NCIt definition : Neuromedin-B receptor (390 aa, 43 kDa) is encoded by the human NMBR gene. This protein is involved in both peptide hormone binding and G protein-coupled receptor signaling.;

NCIt note : A mammalian homolog of amphibian bombesin, Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue.;

Details

Origin ID

C28564;

UMLS CUI

C5234938;

OMIM relation
- Neuromedin b receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, bombesin [MeSH concept]
- receptors, bombesin [MeSH Descriptor]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- NMBR Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epididymis [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Protein Hormone Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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