Protein Hormone Receptor

Preferred Label : Protein Hormone Receptor;

NCIt definition : Typically associated with the cell membrane, Protein Hormone Receptors selectively bind with high affinity to genetically-encoded polymerized amino acids in peptide linkage that have regulatory effects on the activity of specific target cells. A ligand-induced conformational and functional change in the receptor alters its interaction with target molecules, leading to changes in cellular physiology through modification of the activity of signal transduction pathways.;

Details

Origin ID

C18968;

UMLS CUI

C1335534;

Biochemical function of gene products
- Anti-Muellerian Hormone Type-2 Receptor [NCIt concept]
- Leptin Receptor [NCIt concept]
- Melanocortin Receptor 4 [NCIt concept]
- Melanocyte-Stimulating Hormone Receptor [NCIt concept]
- Neuromedin-B Receptor [NCIt concept]
- Neuropeptide S Receptor [NCIt concept]
- SSTR2 Gene Product [NCIt concept]
- Somatostatin Receptor [NCIt concept]
- Somatostatin Receptor Type 1 [NCIt concept]
- Somatostatin Receptor Type 2 [NCIt concept]
- Somatostatin Receptor Type 2b [NCIt concept]
- Somatostatin Receptor Type 3 [NCIt concept]
- Somatostatin Receptor Type 4 [NCIt concept]
- Somatostatin Receptor Type 5 [NCIt concept]
- Vasopressin Receptor [NCIt concept]
- Vasopressin V1A Receptor [NCIt concept]
- Vasopressin V1B Receptor [NCIt concept]
- Vasopressin V2 Receptor [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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