Somatostatin Receptor Type 2

Preferred Label : Somatostatin Receptor Type 2;

NCIt synonyms : SSTR2; Somatostatin Receptor-2; Somatostatin Receptor 2; SSR2a; SSR(2(a)); Somatostatin Receptor Type 2 Isoform A; SS2-R; SS2R; SS-2-R; SSTR2A; Somatostatin Receptor Subtype 2a; SRIF-1;

NCIt definition : Somatostatin receptor type 2 (369 aa, 41 kDa) is encoded by the human SSTR2 gene. This protein is involved in brain development, G protein-coupled receptor signaling, and the inhibition of cell proliferation.;

NCIt note : SSTR2 appears to antagonize SSTR5, and vice versa, suggesting a tissue-specific function and interaction between these receptors.;

Details

Origin ID

C17922;

UMLS CUI

C3501617;

OMIM relation
- Somatostatin receptor 2 [OMIM gene]
See also inter- (CISMeF)
- Somatostatin receptor 2 [OMIM gene]
- somatostatin receptor 2 [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- SSTR2 protein, human [MeSH concept]
- SSTR2 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- SSTR2 protein, human [MeSH Supplementary Concept]
- SSTR2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- SSTR2 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Cerebral Hemisphere [NCIt concept]
- Kidney [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Protein Hormone Receptor [NCIt concept]
- Somatostatin Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
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