Preferred Label : Octreotide Acetate;
NCIt synonyms : Longastatin; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide
cyclic (2- 7)-disulfide Acetate; Sandostatin LAR;
NCIt related terms : D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hyroxymethyl)propyl]-L-cysteinamide,
Cyclic (2- 7)-disulfide, Acetate (Salt); Sandostatin;
NCIt definition : The acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic
properties mimicking those of the natural hormone somatostatin. Octreotide is a more
potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar
to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing
hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin,
vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and
thyroid stimulating hormone.;
UNII : 75R0U2568I;
InChIKey : QWFYIFWTVZFPRY-LODIGNQBSA-N;
CAS number : 79517-01-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 79517-01-4
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G-SRS /a ;
Drug name : Sandostatin Lar Depot; Sandostatin; Longastatina; Sandostatine; Samilstin; Sandostatina;
Molecule name : SMS 201-995 AC; SMS 201-995;
Chemical formula : C49H66N10O10S2.C2H4O2;
NSC code : 671663;
Codes from synonyms : NSC0671663; NSC0672461; 20587;
Origin ID : C53447;
UMLS CUI : C0724649;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
- has_free_acid_or_base_form
- has_target
- is_component_of_chemotherapy_regimen
- is_salt_form_of
