Octreotide Acetate

Preferred Label : Octreotide Acetate;

NCIt synonyms : Longastatin; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2- 7)-disulfide Acetate; Sandostatin LAR; SMS 201-995 AC; SMS 201-995;

NCIt related terms : D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hyroxymethyl)propyl]-L-cysteinamide, Cyclic (2- 7)-disulfide, Acetate (Salt); Sandostatin;

NCIt definition : The acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone.;

UNII : 75R0U2568I;

InChIKey : QWFYIFWTVZFPRY-LODIGNQBSA-N;

CAS number : 79517-01-4;

Drug name : Sandostatin Lar Depot; Sandostatin; Longastatina; Sandostatine; Samilstin; Sandostatina; Mycapssa;

Chemical formula : C49H66N10O10S2.C2H4O2;

NSC code : 671663;

Codes from synonyms : NSC0671663; NSC0672461; 20587;

Details

Origin ID

C53447;

UMLS CUI

C0724649;

Automatic exact mappings (from CISMeF team)
- octreotide [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Octreotide [NCIt concept]
has_target
- Somatostatin Receptor Type 2 [NCIt concept]
- Somatostatin Receptor Type 5 [NCIt concept]
is_component_of_chemotherapy_regimen
- Everolimus/Octreotide Long-acting Release Regimen [NCIt concept]
- Octreotide Long-acting Release Regimen [NCIt concept]
- Octreotide Regimen [NCIt concept]
- Octreotide/Octreotide Long-acting Release Regimen [NCIt concept]
- Octreotide/Octreotide Long-acting Release/Prednisone Regimen [NCIt concept]
is_salt_form_of
- Octreotide [NCIt concept]

Keyword's position in hierarchy(ies) :

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