Preferred Label : Octreotide;
NCIt synonyms : D-Phenylalanyl-L-cysteinyl-L-phenyl-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide
Cyclic (2- 7)-Disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol
Cyclic (2- 7)-Disulfide;
NCIt related terms : D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hyroxymethyl)propyl]-L-cysteinamide,
Cyclic (2- 7)-disulfide;
NCIt definition : A synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking
those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of
growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin,
this agent also suppresses the luteinizing hormone response to gonadotropin-releasing
hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin,
vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and
thyroid stimulating hormone.;
Alternative definition : NCI-GLOSS: A drug similar to the naturally occurring growth hormone inhibitor somatostatin.
Octreotide is used to treat diarrhea and flushing associated with certain types of
tumors.;
UNII : RWM8CCW8GP;
InChIKey : DEQANNDTNATYII-OULOTJBUSA-N;
CAS number : 83150-76-9;
Molecule name : SMS-201-995; SMS 201 995; SMS 201995;
Chemical formula : C49H66N10O10S2;
ChEBI ID : CHEBI:7726;
Codes from synonyms : CDR0000045141; 02189; 362;
PubMed : 16917205;
Origin ID : C711;
UMLS CUI : C0028833;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- has_target
- is_component_of_chemotherapy_regimen
- is_free_acid_or_base_form_of
