Octreotide Pamoate

Preferred Label : Octreotide Pamoate;

NCIt synonyms : Octreotide Embpnate; OP LAR;

NCIt related terms : SMS 201-995 pa LAR;

NCIt definition : A synthetic long-acting octapeptide analogue of endogenous somatostatin. Octreotide pamoate binds to somatostatin receptors expressed by some neuroendocrine and non-neuroendocrine tumor cells, thereby initiating somatostatin receptor-mediated apoptosis. Other possible antineoplastic activities of this agent include suppression of tumor angiogenesis and tumor growth-promoting insulin-like growth factor 1 (IGF-1). (NCI04);

UNII : MWH8YQ1AIO;

InChIKey : KFWJVABDRRDUHY-XJQYZYIXSA-N;

CAS number : 135467-16-2;

Drug name : OncoLar;

Molecule name : SMS 201-995 pa LAR; SMS 201-995 PA;

Chemical formula : C49H66N10O10S2.C23H16O6;

NSC code : 685403;

Codes from synonyms : 50546; NSC0685403;

Details

Origin ID

C2402;

UMLS CUI

C0338271;

Currated CISMeF NLP mapping
- OCTREOTIDE PAMOATE [SMS substance]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Somatostatin Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Receptor Activation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Positive Regulation of Apoptosis [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Octreotide [NCIt concept]
has_target
- Somatostatin Receptor Type 2 [NCIt concept]
- Somatostatin Receptor Type 5 [NCIt concept]
is_component_of_chemotherapy_regimen
- Cyclophosphamide/Doxorubicin/Octreotide Pamoate/Tamoxifen [NCIt concept]
- Fluorouracil/Octreotide Pamoate [NCIt concept]
- Octreotide Pamoate/Tamoxifen [NCIt concept]
is_salt_form_of
- Octreotide [NCIt concept]

Keyword's position in hierarchy(ies) :

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