" /> Tidutamab - CISMeF





Preferred Label : Tidutamab;

NCIt synonyms : Anti-SSTR2 x Anti-CD3 Monoclonal Antibody XmAb18087;

NCIt definition : A humanized, Fc domain-containing, bispecific monoclonal antibody targeting human CD3, a T-cell surface antigen, and somatostatin receptor 2 (SSTR2), a tumor-associated antigen (TAA) expressed on certain cancer cells, with potential antineoplastic activity. Upon administration, tidutamab binds to both T-cells and SSTR2-expressing cancer cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against the SSTR2-expressing cancer cells. The inclusion of an Fc domain on the antibody prolongs the half-life of the bispecific antibody.;

UNII : 88635FW2QX;

CAS number : 2148354-90-7;

Molecule name : XmAb 18087; XmAb-18087;

NCI Metathesaurus CUI : CL544867;

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13/07/2025


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