NCIt synonyms : Anti-SSTR2 x Anti-CD3 Monoclonal Antibody XmAb18087;
NCIt definition : A humanized, Fc domain-containing, bispecific monoclonal antibody targeting human
CD3, a T-cell surface antigen, and somatostatin receptor 2 (SSTR2), a tumor-associated
antigen (TAA) expressed on certain cancer cells, with potential antineoplastic activity.
Upon administration, tidutamab binds to both T-cells and SSTR2-expressing cancer cells.
The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response
against the SSTR2-expressing cancer cells. The inclusion of an Fc domain on the antibody
prolongs the half-life of the bispecific antibody.;
UNII : 88635FW2QX;
CAS number : 2148354-90-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2148354-90-7
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G-SRS /a ;
Semantic type(s)