Preferred Label : Lanreotide Long-Acting Aqueous Gel;
NCIt synonyms : lanreotide (long-acting aqueous preparation); Lanreotide Autogel;
NCIt definition : A long-acting aqueous gel preparation of lanreotide, a synthetic cyclic octapeptide
analogue of somatostatin. Lanreotide inhibits the secretion of growth hormone (GH)
by binding to pituitary somatostatin receptors, and may inhibit the release of various
other hormones, including thyroid stimulating hormone (TSH) and the gastroenteropancreatic
hormones insulin, glucagon and gastrin. This agent also decreases circulating total
and free insulin-like growth factor 1 (IGF-I). Lanreotide exhibits a high binding
affinity for somatostatin receptor 2 (SSTR-2) and a lesser binding affinity for SSTR-5.
However, compared to octreotide, this agent is less potent in inhibiting the release
of growth hormone from the pituitary gland.;
Drug name : Somatuline Autogel;
Origin ID : C65111;
UMLS CUI : C1831852;
Semantic type(s)
- concept_is_in_subset
- has_target
