Preferred Label : G Protein-Coupled Receptor Gene;
NCIt synonyms : GPR; GPCR; G Protein Coupled Receptor Gene; G-Protein Coupled Receptor Gene;
NCIt definition : These genes encodes G protein-coupled receptors (GPRs or GPCRs). GPRs contain 7 hydrophobic
transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce
a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular
effects via G proteins. (from OMIM 604161);