C-X-C Chemokine Receptor Type 3

Preferred Label : C-X-C Chemokine Receptor Type 3;

NCIt synonyms : G Protein-Coupled Receptor 9; Mig Receptor; IP10 Receptor; CXCR3; G-Protein Coupled Receptor 9; C-X-C Motif Chemokine Receptor-3; CKR-L2; CD183; CXCR-3; Interferon-Inducible Protein 10 Receptor; CD183 Antigen; CXC-R3;

NCIt definition : C-X-C chemokine receptor type 3 (368 aa, 41 kDa) is encoded by the human CXCR3 gene. This protein plays a role in cell proliferation, cell survival and angiogenesis.;

NCIt note : Three isoforms of C-X-C chemokine receptor type 3 are expressed because of alternative splicing. Each isoform differs in ligand-specificity. (UniProt);

Details

Origin ID

C26227;

UMLS CUI

C1741914;

OMIM relation
- Chemokine, cxc motif, receptor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CXCR3 protein, human [MeSH concept]
- CXCR3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CXCR3 Gene [NCIt concept]
- Chemokine Receptor Gene [NCIt concept]
- Cytokine Receptor Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- Calpain-2 Cell Motility Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- NO2-Dependent IL12 Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Motility [NCIt concept]
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients