Histamine H2 Receptor

Preferred Label : Histamine H2 Receptor;

NCIt synonyms : Histamine Receptor H2; Gastric Receptor I; H2R; HRH2; Histamine-2 Receptor; HH2R; Gastric Receptor 1; Histamine Receptor-H2;

NCIt definition : Histamine H2 receptor (359 aa, 40 kDa) is encoded by the human HRH2 gene. This protein is involved in the regulation of gastric acid secretion, gastrointestinal motility, and intestinal secretion.;

Details

Origin ID

C41020;

UMLS CUI

C1531432;

Currated CISMeF NLP mapping
- Histamine H2 receptor (substance) [SNOMED CT concept]
- receptors, histamine H2 [MeSH concept]
- receptors, histamine h2 [MeSH Descriptor]
OMIM relation
- Histamine receptor h2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- HRH2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Gastric Acid Secretion Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Cimetidine [NCIt concept]
- Famotidine [NCIt concept]

Keyword's position in hierarchy(ies) :

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