NCIt definition : A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a
competitive inhibitor of histamine H2-receptors located on the basolateral membrane
of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion,
resulting in a reduction in gastric volume, acidity, and amount of gastric acid released
in response to various stimuli.;