receptors, histamine h2

Preferred Label : receptors, histamine h2;

MeSH definition : A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5);

MeSH synonym : histamine h2 receptors; receptors, h2; h2 receptors, histamine; h2 receptors;

MeSH annotation : receptors for the non-classical antihistaminics (HISTAMINE H2 ANTAGONISTS); DF: RECEPT H2; receptors for the non-classical antihistaminics (HISTAMINE H2 ANTAGONISTS);

Is substance : O;

Details

Origin ID

D011970;

UMLS CUI

C0034815;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Currated CISMeF NLP mapping
- Histamine H2 Receptor [NCIt concept]
- Histamine H2 receptor (substance) [SNOMED CT concept]
Indexing information
- 4-methylhistamine [MeSH Supplementary Concept]
- BU-E 75 [MeSH Supplementary Concept]
- FR-A 19 [MeSH Supplementary Concept]
- VUF 8414 [MeSH Supplementary Concept]
- diphenethindole [MeSH Supplementary Concept]
Record concept(s)
- receptors, histamine H2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- Hrh2 protein, mouse [MeSH Supplementary Concept]
- tidazin [MeSH Supplementary Concept]
Related MeSH term(s)
- histamine agonists [MeSH Descriptor]
- histamine h2 antagonists [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- H2 receptor [FMA entity]
- Histamine H2 receptor (substance) [SNOMED CT concept]
- histamine h2 receptor site [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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