" /> Cimetidine - CISMeF





Preferred Label : Cimetidine;

NCIt synonyms : N-Cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine; Guanidine, N''-Cyano-N-Methyl-N'-(2-(((5-Methyl-1H-Imidazol-4-yl)Methyl)Thio)Ethyl)-;

NCIt related terms : Tagamet;

NCIt definition : A histamine H(2)-receptor antagonist. Enhancing anti-tumor cell-mediated responses, cimetidine blocks histamine's ability to stimulate suppressor T lymphocyte activity and to inhibit natural killer (NK) cell activity and interleukin-2 production. Cimetidine also may inhibit tumor growth by suppressing histamine's growth-factor activity and blocking histamine-induced stimulation of vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor. (NCI04);

Alternative definition : NCI-GLOSS: A drug usually used to treat stomach ulcers and heartburn. It is also commonly used in a regimen to prevent allergic reactions.;

UNII : 80061L1WGD;

InChIKey : AQIXAKUUQRKLND-UHFFFAOYSA-N;

CAS number : 51481-61-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 51481-61-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Tagamet;

Chemical formula : C10H16N6S;

NSC code : 335308;

ChEBI ID : CHEBI:3699;

Codes from synonyms : NSC0335308; 01655; CDR0000045184; 103;

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16/05/2024


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