Atypical Chemokine Receptor 3

Preferred Label : Atypical Chemokine Receptor 3;

NCIt synonyms : CXC-R7; G-Protein Coupled Receptor RDC1 Homolog; G-Protein Coupled Receptor 159; Chemokine Orphan Receptor 1; CXCR-7; RDC-1; CXCR7; CMKOR1; G Protein-Coupled Receptor 159; C-X-C Chemokine Receptor Type 7; ACKR3;

NCIt definition : Atypical chemokine receptor 3 (362 aa, 41 kDa) is encoded by the human ACKR3 gene. This protein is involved in the negative regulation of chemokine signaling.;

NCIt note : Stromal cell-derived factor 1 appears to be a ligand for C-X-C chemokine receptor type 7.;

Details

Origin ID

C91371;

UMLS CUI

C1259316;

OMIM relation
- Atypical chemokine receptor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- ACKR3 protein, human [MeSH concept]
- ACKR3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ACKR3 Gene [NCIt concept]
- Chemokine Receptor Gene [NCIt concept]
- Cytokine Receptor Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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