Preferred Label : Vasoactive Intestinal Polypeptide Receptor 1;
NCIt synonyms : VIPR1; RDC1; VIP Receptor, Type I; PACAP Receptor, Type II; VIP and PACAP Receptor 1; VIPR; PACAP-R2; Pituitary Adenylate Cyclase-Activating Polypeptide Receptor, Type II; PACAP Type II Receptor; Pituitary Adenylate Cyclase Activating Polypeptide Type II Receptor; PACAP-R-2; VPAC1; Vasoactive Intestinal Peptide Receptor 1; Pituitary Adenylate Cyclase-Activating Polypeptide Type II Receptor; Vasoactive Intestinal Peptide Receptor-1; VIP-R-1;
NCIt definition : Vasoactive intestinal polypeptide receptor 1 (457 aa, 52 kDa) is encoded by the human
VIPR1 gene. This protein plays a role in G protein-coupled receptor signaling, digestion,
muscle contraction and the regulation of cell proliferation.;
NCIt note : Encoded by human VIPR1 Gene (GPCR Family 2), Vasoactive Intestinal Peptide Receptor
1 appears to be expressed in brain, heart, kidney, liver, colonic epithelia, and placenta.
The 457-amino acid 51.5 kD (precursor) G protein-coupled receptor contains seven transmembrane
domains. Distinct subsets of neural, respiratory, gastrointestinal, and immune cells
bear high-affinity VIP G protein receptors, capable of activating adenylate cyclase.
(OMIM, Swiss-Prot, LocusLink, and NCI);
Origin ID : C21443;
UMLS CUI : C0534281;
OMIM relation
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- gene_encodes_gene_product
- gene_product_expressed_in_tissue
- gene_product_has_associated_anatomy
- gene_product_has_biochemical_function
- gene_product_has_chemical_classification
- gene_product_has_structural_domain_or_motif
- gene_product_is_element_in_pathway
- gene_product_plays_role_in_biological_process
- is_target
