Preferred Label : Copper Cu 64 TP3805;
NCIt synonyms : Cu-64-TP3805;
NCIt definition : A peptide analog of pituitary adenylate cyclase-activating peptide (PACAP) radiolabeled
with the positron-emitting radioisotope copper Cu 64, with potential diagnostic ability
upon positron emission tomography (PET) imaging. The peptide moiety of copper Cu 64
TP3805 is able to bind to vasoactive intestinal peptide/pituitary adenylate cyclase
activating peptide receptors 1 (VPAC1). Upon PET imaging, the cancer cells expressing
VPAC1 can be visualized and may allow for early detection. The oncogenic product VPAC1
is overexpressed in a variety of cancer cell types, moreover, it is overexpressed
in 100% of breast tumors at the onset of the cancer. Compared to other positron-emitting
radioisotopes, Cu 64 has a longer half life.;
NCI Metathesaurus CUI : CL432407;
Origin ID : C98289;
UMLS CUI : C3273940;
Semantic type(s)
- concept_is_in_subset
- has_target
