Adhesion G Protein-Coupled Receptor E2

Preferred Label : Adhesion G Protein-Coupled Receptor E2;

NCIt synonyms : CD312; EGF-Like Module-Containing Mucin-Like Hormone Receptor-Like 2; ADGRE2; CD312 Antigen; EGF-Like Module Receptor 2;

NCIt definition : Adhesion G protein-coupled receptor E2 (823 aa, 90 kDa) is encoded by the human ADGRE2 gene. This protein is involved in chondroitin sulfate binding and in myeloid cell adhesion and migration.;

Details

Origin ID

C200348;

OMIM relation
- Adhesion g protein-coupled receptor e2 [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ADGRE2 Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Myeloid Cell [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Matrix Adhesion Process [NCIt concept]
- Chemotactic Process [NCIt concept]
- Degranulation [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Inflammatory Response [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- CLEC12A-targeting CCR/Anti-ADGRE2 CAR T Cells ADCLEC.syn1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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