Atypical Chemokine Receptor 4

Preferred Label : Atypical Chemokine Receptor 4;

NCIt synonyms : CCX-CKR; PPR1; CCRL1; CCR11; Chemokine (C-C Motif) Receptor-Like 1; CC-CKR-11; CCBP2; C-C CKR-11; VSHK1; Chemokine Receptor-Like 1; CCRL1 Protein; CCR-11; C-C Chemokine Receptor Type 11; CCX CKR; C-C Chemokine Receptor-Like 1; C-C Motif Chemokine Receptor-Like 1 Protein; ACKR4;

NCIt definition : Atypical chemokine receptor 4 (350 aa, 40 kDa) is encoded by the human ACKR4 gene. This protein plays a role in chemokine sequestration.;

NCIt note : Chemokine (C-C Motif) Receptor-Like 1, a 45-kD glycosylated protein encoded by the CCRL1 gene, is a G protein-coupled receptor that binds chemokines of the CC subfamily, especially MCP-4, ELC (SCYA19) and TECK (SCYA25). CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines. (LocusLink, OMIM);

Details

Origin ID

C25788;

UMLS CUI

C1438953;

OMIM relation
- Atypical chemokine receptor 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- ACKR4 protein, human [MeSH concept]
- ACKR4 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ACKR4 Gene [NCIt concept]
- Chemokine Receptor Gene [NCIt concept]
- Cytokine Receptor Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Fetus [NCIt concept]
- Heart [NCIt concept]
- Lung [NCIt concept]
- Pancreas [NCIt concept]
- Spleen [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immune Response Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Skeletal Development [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients