Frizzled-1 - CISMeF

Preferred Label : Frizzled-1;

NCIt synonyms : hFz1; FzE1; Fz-1; Frizzled 1; Frizzled Homolog 1; Frizzled Family Receptor 1;

NCIt definition : Frizzled-1 (647 aa, 71 kDa) is encoded by the human FZD1 gene. This protein is involved in the regulation of Wnt protein signaling.;

Details

Origin ID

C91368;

UMLS CUI

C1454919;

OMIM relation
- Frizzled class receptor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- FZD1 protein, human [MeSH concept]
- FZD1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- FZD1 Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Frizzled Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Basal Cell Carcinoma Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Pitx2 Transcription Regulation Pathway [NCIt concept]
- Presenilin Action in Notch and Wnt Signaling Pathways [NCIt concept]
- Segmentation Clock Pathway [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- Wnt/LRP6 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Vantictumab [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients