Vasopressin Receptor

Preferred Label : Vasopressin Receptor;

NCIt synonyms : AVPR; Arginine Vasopressin Receptor;

NCIt definition : The biologic effects of arginine vasopressin (AVP) are mediated by 3 receptor subtypes: the V1A and V1B receptors that activate phospholipases via G alpha (q/11), and the V2 receptor that activates adenylyl cyclase by interacting with G alpha (s). This subfamily of G-protein coupled receptors also includes OXT receptors. Their activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. All are involved in the control of body fluid osmolality, blood volume, blood pressure, and vascular tone. (from OMIM);

Details

Origin ID

C17345;

UMLS CUI

C0078077;

Currated CISMeF NLP mapping
- receptors, vasopressin [MeSH Descriptor]
- receptors, vasopressin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, vasopressin [MeSH concept]
- receptors, vasopressin [MeSH Descriptor]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Protein Hormone Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Signaling [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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