Hydroxycarboxylic Acid Receptor 3

Preferred Label : Hydroxycarboxylic Acid Receptor 3;

NCIt synonyms : GPR109B; Putative G Protein-Coupled Receptor HM74; Putative Chemokine Receptor, GTP-Binding Protein; Chemokine Receptor HM74; HM74; HM74 Protein; G-Protein Coupled Receptor 109B; G Protein-Coupled Receptor 109B; Hydroxy-Carboxylic Acid Receptor 3; Chemokine Receptor-HM74; Niacin Receptor 2; Nicotinic Acid Receptor 2; G-Protein Coupled Receptor HM74B; G-Protein Coupled Receptor HM74;

NCIt definition : Hydroxycarboxylic acid receptor 3 (387 aa, 44 kDa) is encoded by the human HCAR3 gene. This protein is involved in G protein-coupled receptor signaling and lipid metabolism.;

NCIt note : Hydroxycarboxylic acid receptor 3 mediates anti-lipolytic responses to increased rates of beta-oxidation. (UniProt);

Details

Origin ID

C26305;

UMLS CUI

C1176162;

OMIM relation
- Hydroxycarboxylic acid receptor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- HCAR3 protein, human [MeSH concept]
- HCAR3 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- HCAR3 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Adipose Tissue [NCIt concept]
- Neutrophil [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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