KiSS-1 Receptor

Preferred Label : KiSS-1 Receptor;

NCIt synonyms : Metastin Receptor; G-Protein-Coupled Receptor GPR54; G Protein-Coupled Receptor AXOR12; GPR54; GPR54 Metastin Receptor; G-Protein Coupled Receptor OT7T175; G Protein-Coupled Receptor-54-1; Hypogonadotropin-1; hOT7T175; G-Protein Coupled Receptor 54; KiSS-1R; Kisspeptins Receptor; G Protein-Coupled Receptor 54;

NCIt definition : KiSS-1 receptor (398 aa, 43 kDa) is encoded by the human KISS1R gene. This protein plays a role in the onset of puberty and the suppression of tumor metastasis.;

NCIt note : Encoded by human GPR54 Gene, 395-aa 43-kDa G Protein-Coupled Receptor 54 is a Gq/11-coupled receptor for endogenous KISS1 (Metastin), which appears to inhibit chemotaxis.;

Details

Origin ID

C29643;

UMLS CUI

C1097812;

OMIM relation
- Kiss1 receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- KISS1R protein, human [MeSH Supplementary Concept]
- KISS1R protein, human [MeSH concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- KISS1R Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
- Metastasis Suppressor Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Metastasis Suppression [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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