5-Hydroxytryptamine Receptor 3A

Preferred Label : 5-Hydroxytryptamine Receptor 3A;

NCIt synonyms : HTR3; 5-HT3R; 5-Hydroxytryptamine 3 Receptor; Serotonin-Gated Ion Channel Receptor; 5HT3R; Serotonin Receptor 3A; HTR3 Protein; HTR3A; 5-Hydroxytryptamine (Serotonin) Receptor-3; 5-Hydroxytryptamine Receptor 3; Serotonin-5-HT-3 Receptor; 5-HT-3; 5-hydroxytryptamine (Serotonin) Receptor 3A; Serotonin 5-HT-3 Receptor;

NCIt definition : 5-hydroxytryptamine receptor 3A (478 aa, 55 kDa) is encoded by the human HTR3A gene. This protein plays a role in serotonin-dependent depolarization in neurons.;

NCIt note : To form an active ligand-gated channel, 5-hydroxytryptamine receptor 3A can form a homopentameric complex or a heteropentameric complex with HTR3B or HTR3C or HTR3D or HTR3E. (UniProt);

Details

Origin ID

C25906;

UMLS CUI

C1700654;

OMIM relation
- 5-hydroxytryptamine receptor 3a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- HTR3A protein, human [MeSH concept]
- HTR3A protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- G Protein-Coupled Receptor Gene [NCIt concept]
- HTR3A Gene [NCIt concept]
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Granisetron Hydrochloride [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Ion Channel [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Gated Ion Channel [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_physical_part_of
- 5-HT3 Receptor [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
is_target
- Ondansetron [NCIt concept]
- Ondansetron Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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