5-HT3 Receptor

Preferred Label : 5-HT3 Receptor;

NCIt synonyms : 5-HT-3 Receptor; Serotonin Receptor Type 3; Serotonin 5-HT-3 Receptor; 5-Hydroxytryptamine 3 Receptor; 5HT3R; 5-HT3R; Type 3 Serotonin Receptor; 5-HT-3R; 5HT3 Receptor;

NCIt definition : A protein complex that plays a role in neurotransmitter-gated ion transport. It is a pentamer that binds serotonin and is comprised of either five 5-hydroxytryptamine receptor 3A subunits or a combination of four 5-hydroxytryptamine receptor 3A molecules with one of the alternative subunits, 5-hydroxytryptamine receptor 3B, 3C, 3D or 3E.;

NCIt note : The 5-HT3 receptor is a non-selective, cation-specific, ligand-gated ion channel. (UniProt);

Details

Origin ID

C105979;

UMLS CUI

C0295352;

Currated CISMeF NLP mapping
- receptors, serotonin, 5-HT3 [MeSH concept]
- receptors, serotonin, 5-ht3 [MeSH Descriptor]
See also inter- (CISMeF)
- 5-hydroxytryptamine receptor 3a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, serotonin, 5-HT3 [MeSH concept]
- receptors, serotonin, 5-ht3 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- Gated Ion Channel [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Ion Channel Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Neuronal Transmission [NCIt concept]
- Receptor Signaling [NCIt concept]
has_gene_product_element
- 5-Hydroxytryptamine Receptor 3A [NCIt concept]
is_target
- Fosnetupitant/Palonosetron Hydrochloride [NCIt concept]
- Granisetron Hydrochloride [NCIt concept]
- Granisetron Transdermal Patch [NCIt concept]
- Ondansetron [NCIt concept]
- Ondansetron Hydrochloride [NCIt concept]
- Tropisetron [NCIt concept]

Keyword's position in hierarchy(ies) :

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