Tropisetron - CISMeF

Preferred Label : Tropisetron;

NCIt definition : An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting. (NCI04);

Alternative definition : NCI-GLOSS: A substance used to treat nausea and vomiting caused by cancer treatment. It is not available in the United States. Tropisetron is a type of serotonin receptor antagonist and a type of antiemetic.;

UNII : 6I819NIK1W;

InChIKey : ZNRGQMMCGHDTEI-ITGUQSILSA-N;

CAS number : 89565-68-4;

Molecule name : ICS 205-930; ICS 205 930;

Chemical formula : C17H20N2O2;

Codes from synonyms : CDR0000302469; 519;

Details

Origin ID

C1131;

UMLS CUI

C0063322;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tropisetron (medicinal product) [SNOMED CT concept]
- Tropisetron [MeSH Descriptor]
- Tropisetron (substance) [SNOMED CT concept]
- tropisetron [ATC Code]
- tropisetron [MeSH concept]
Validated automatic mappings to BTNT
- tropisetron [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Tropisetron Hydrochloride [NCIt concept]
has_target
- 5-HT3 Receptor [NCIt concept]
is_free_acid_or_base_form_of
- Tropisetron Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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