Preferred Label : Granisetron Transdermal Patch;
NCIt synonyms : Granisetron Transdermal System; 1-Methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide;
NCIt definition : A transdermal system containing granisetron, a selective serotonin (5-HT) receptor
antagonist, with antiemetic activity. Upon application of the transdermal patch to
the skin and subsequent release into the bloodstream, granisetron selectively binds
to and blocks the 5-HT subtype 3 (5-HT3) receptors located in the vagus nerve terminal
and in the vomiting center in the central nervous system (CNS). By preventing stimulation
of 5-HT3 receptors, this agent is able to suppress chemotherapy-induced nausea and
vomiting.;
CAS number : 109889-09-0;
Drug name : Sancuso;
Origin ID : C80377;
UMLS CUI : C2365254;
Semantic type(s)
- concept_is_in_subset
- has_target
