Alpha-1B Adrenergic Receptor

Preferred Label : Alpha-1B Adrenergic Receptor;

NCIt synonyms : ADRA1B; Alpha-1B Adrenoceptor; Alpha-1B-Adrenergic Receptor; Alpha-1B Adrenoreceptor; Alpha-1-Adrenergic Receptor;

NCIt definition : Alpha-1B adrenergic receptor (520 aa, 57 kDa) is encoded by the human ADRA1B gene. This protein plays a role in cell signaling, cell proliferation and heart development.;

NCIt note : Alpha-1B Adrenergic Receptor is a Gq/11-associated integral membrane protein that activates mitogenic PI-calcium second messenger responses and controls vascular tone and systolic blood pressure.;

Details

Origin ID

C20935;

UMLS CUI

C2932396;

Currated CISMeF NLP mapping
- receptor, adrenergic, alpha-1B [MeSH concept]
OMIM relation
- Alpha-1b-adrenergic receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- ADRA1B protein, human [MeSH concept]
- ADRA1B protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ADRA1B Gene [NCIt concept]
- Alpha Adrenergic Receptor Gene [NCIt concept]
- G Protein-Coupled Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Adrenergic Receptor [NCIt concept]
- Cell Surface Receptor [NCIt concept]
- Guanine Nucleotide Exchange Factor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Phospholipid Associated Cell Signaling Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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